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MedKoo Cat#: 573867 | Name: Aminacrine pyruvate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aminacrine pyruvate is a highly fluorescent anti-infective dye used as a topical antiseptic and mutagen due to its interaction with DNA. It is also used as an intracellular pH indicator.

Chemical Structure

Aminacrine pyruvate
Aminacrine pyruvate
CAS#25332-08-5 (pyruvate)

Theoretical Analysis

MedKoo Cat#: 573867

Name: Aminacrine pyruvate

CAS#: 25332-08-5 (pyruvate)

Chemical Formula: C16H14N2O3

Exact Mass: 0.0000

Molecular Weight: 282.30

Elemental Analysis: C, 68.08; H, 5.00; N, 9.92; O, 17.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
90-45-9 (free base) 134-50-9 (HCl) 52417-22-8 (HCl hydrate) 25332-08-5 (pyruvate) 17162-18-4 (undecylate)
Synonym
Aminacrine pyruvate
IUPAC/Chemical Name
Propanoic acid, 2-oxo-, compd. with 9-acridinamine (1:1)
InChi Key
OODMFCDELLGINE-UHFFFAOYSA-N
InChi Code
1S/C13H10N2.C3H4O3/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;1-2(4)3(5)6/h1-8H,(H2,14,15);1H3,(H,5,6)
SMILES Code
CC(=O)C(=O)O.c1ccc2c(c1)c(c3ccccc3n2)N
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 282.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Cerón-Carrasco JP, Ruiz J, Vicente C, de Haro C, Bautista D, Zúñiga J, Requena A. DFT Simulation of Structural and Optical Properties of 9-Aminoacridine Half-Sandwich Ru(II), Rh(III), and Ir(III) Antitumoral Complexes and Their Interaction with DNA. J Chem Theory Comput. 2017 Aug 8;13(8):3898-3910. doi: 10.1021/acs.jctc.7b00139. Epub 2017 Jul 6. PubMed PMID: 28641006. 2: Ishigami-Yuasa M, Watanabe Y, Mori T, Masuno H, Fujii S, Kikuchi E, Uchida S, Kagechika H. Development of WNK signaling inhibitors as a new class of antihypertensive drugs. Bioorg Med Chem. 2017 Jul 15;25(14):3845-3852. doi: 10.1016/j.bmc.2017.05.034. Epub 2017 May 19. PubMed PMID: 28566208. 3: Xiao S, Wang T, Ma X, Qin Y, Li X, Zhao Z, Liu X, Wang X, Xie H, Jiang Q, Sun L, Luo B, Shang L, Chen W, Bai Y, Tang M, He M, Wu L, Ma Q, Hou D, He J. Efficacy and safety of a novel acetylcholinesterase inhibitor octohydroaminoacridine in mild-to-moderate Alzheimer's disease: a Phase II multicenter randomised controlled trial. Age Ageing. 2017 Sep 1;46(5):767-773. doi: 10.1093/ageing/afx045. PubMed PMID: 28419192. 4: Zhou D, Guo S, Zhang M, Liu Y, Chen T, Li Z. Mass spectrometry imaging of small molecules in biological tissues using graphene oxide as a matrix. Anal Chim Acta. 2017 Apr 15;962:52-59. doi: 10.1016/j.aca.2017.01.043. Epub 2017 Jan 31. PubMed PMID: 28231880. 5: Campbell AP, Wakelin LP, Denny WA, Finch AM. Homobivalent Conjugation Increases the Allosteric Effect of 9-aminoacridine at the α1-Adrenergic Receptors. Mol Pharmacol. 2017 Feb;91(2):135-144. doi: 10.1124/mol.116.105874. Epub 2016 Nov 30. PubMed PMID: 27903755. 6: Kava HW, Murray V. CpG methylation increases the DNA binding of 9-aminoacridine carboxamide Pt analogues. Bioorg Med Chem. 2016 Oct 1;24(19):4701-4710. doi: 10.1016/j.bmc.2016.08.011. Epub 2016 Aug 8. PubMed PMID: 27567075.