AC1NOD4Q | CAS 1992782-24-7

MedKoo Cat#: 565722 | Name: AC1NOD4Q

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AC1NOD4Q is a novel blocker of hox antisense intergenic rna (hotair) by abrogating the scaffold interaction with ezh2

Chemical Structure

AC1NOD4Q

CAS#907554-37-4

Theoretical Analysis

MedKoo Cat#: 565722

Name: AC1NOD4Q

CAS#: 907554-37-4

Chemical Formula: C26H16N6O8

Exact Mass: 540.1030

Molecular Weight: 540.45

Elemental Analysis: C, 57.78; H, 2.98; N, 15.55; O, 23.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

907554-37-4 1992782-24-7 (tauto-isomer) 1339064-67-3 (SR-isomer)

Synonym

AC1NOD4Q; AC1NOD4 1 4; AC1NOD4-1-4; ADQ; NSC-372295; NSC 372295; NSC372295

IUPAC/Chemical Name

2,2'-(1,4-Phenylene)bis(7-nitro-4,9-dihydrofuro[2,3-b]quinoxalin-3(2H)-one)

InChi Key

LFAVZZKNQFFBAI-UHFFFAOYSA-N

InChi Code

InChI=1S/C26H16N6O8/c33-21-19-25(29-17-9-13(31(35)36)5-7-15(17)27-19)39-23(21)11-1-2-12(4-3-11)24-22(34)20-26(40-24)30-18-10-14(32(37)38)6-8-16(18)28-20/h1-10,23-24,27-30H

SMILES Code

O=C1C(C2=CC=C(C(O3)C(C4=C3NC5=C(C=CC([N+]([O-])=O)=C5)N4)=O)C=C2)OC(N6)=C1NC7=C6C=C([N+]([O-])=O)C=C7

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 540.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ren Y, Wang YF, Zhang J, Wang QX, Han L, Mei M, Kang CS. Targeted design and identification of AC1NOD4Q to block activity of HOTAIR by abrogating the scaffold interaction with EZH2. Clin Epigenetics. 2019 Feb 14;11(1):29. doi: 10.1186/s13148-019-0624-2. PubMed PMID: 30764859; PubMed Central PMCID: PMC6376746.