MedKoo Cat#: 573718 | Name: (R)-Allantoin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

(R)-Allantoin is a R-isomer of Allantoin, which is a biochemical. Allantoin, is a diureide of glyoxylic acid. Allantoin is potentionally a treatment for epidermolysis bullosa. Several beneficial effects for allantoin as an active ingredient in over-the-counter cosmetics include: a moisturizing and keratolytic effect, increasing the water content of the extracellular matrix and enhancing the desquamation of upper layers of dead skin cells, increasing the smoothness of the skin; promoting cell proliferation and wound healing; and a soothing, anti-irritant, and skin protectant effect by forming complexes with irritant and sensitizing agents.

Chemical Structure

(R)-Allantoin
(R)-Allantoin
CAS#7303-80-2 (R-isomer)

Theoretical Analysis

MedKoo Cat#: 573718

Name: (R)-Allantoin

CAS#: 7303-80-2 (R-isomer)

Chemical Formula: C4H6N4O3

Exact Mass: 158.0440

Molecular Weight: 158.12

Elemental Analysis: C, 30.39; H, 3.83; N, 35.43; O, 30.36

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Synonym
(-)-Allantoin, Allantoin, (-)-; Allantoin, (R)-(-)-;
IUPAC/Chemical Name
Urea, N-((4R)-2,5-dioxo-4-imidazolidinyl)-
InChi Key
POJWUDADGALRAB-PVQJCKRUSA-N
InChi Code
1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11)/t1-/m1/s1
SMILES Code
[C@@H]1(C(=O)NC(=O)N1)NC(=O)N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 158.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Eslami-Farsani M, Moslehi A, Hatami-Shahmir A. Allantoin improves histopathological evaluations in a rat model of gastritis. Physiol Int. 2018 Dec 1;105(4):325-334. doi: 10.1556/2060.105.2018.4.30. Epub 2018 Dec 23. PubMed PMID: 30582339. 2: Nishinami S, Hirano A, Arakawa T, Shiraki K. Effects of allantoin and dimethyl sulfoxide on the thermal aggregation of lysozyme. Int J Biol Macromol. 2018 Nov;119:180-185. doi: 10.1016/j.ijbiomac.2018.07.043. Epub 2018 Jul 26. PubMed PMID: 30009897. 3: Nishinami S, Yoshizawa S, Arakawa T, Shiraki K. Allantoin and hydantoin as new protein aggregation suppressors. Int J Biol Macromol. 2018 Jul 15;114:497-503. doi: 10.1016/j.ijbiomac.2018.03.011. Epub 2018 Mar 2. PubMed PMID: 29505874.