MedKoo Cat#: 558954 | Name: Azide-PEG4-Amine free base
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Azido-PEG4-amine is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.

Chemical Structure

Azide-PEG4-Amine free base
Azide-PEG4-Amine free base
CAS#134179-38-7 (free base)

Theoretical Analysis

MedKoo Cat#: 558954

Name: Azide-PEG4-Amine free base

CAS#: 134179-38-7 (free base)

Chemical Formula: C8H18N4O3

Exact Mass: 218.1379

Molecular Weight: 218.26

Elemental Analysis: C, 44.03; H, 8.31; N, 25.67; O, 21.99

Price and Availability

Size Price Availability Quantity
1g USD 250.00 Ready to ship
2g USD 450.00 Ready to ship
5g USD 950.00 2 weeks
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Synonym
Azide-PEG4-Amine HCl; Azide-PEG4-Amine free base; Amino-PEG3-C2-Azido
IUPAC/Chemical Name
2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethan-1-amine
InChi Key
FPVCVHVTMPCZTH-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H18N4O3/c9-1-3-13-5-7-15-8-6-14-4-2-11-12-10/h1-9H2
SMILES Code
NCCOCCOCCOCCN=[N+]=[N-]
Appearance
Liquid
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 218.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Wang S, Han L, Han J, Li P, Ding Q, Zhang QJ, Liu ZP, Chen C, Yu Y. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation. Nat Chem Biol. 2019 Dec;15(12):1223-1231. doi: 10.1038/s41589-019-0379-2. Epub 2019 Oct 28. PMID: 31659317; PMCID: PMC6864272.