Oncopterin | CAS#143460-23-5 | pterin

MedKoo Cat#: 584910 | Name: Oncopterin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Oncopterin is found in urine from patients with solid and blood cancers.

Chemical Structure

Oncopterin

CAS#143460-23-5

Theoretical Analysis

MedKoo Cat#: 584910

Name: Oncopterin

CAS#: 143460-23-5

Chemical Formula: C12H18N6O3

Exact Mass: 294.1440

Molecular Weight: 294.32

Elemental Analysis: C, 48.97; H, 6.16; N, 28.56; O, 16.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

Oncopterin

IUPAC/Chemical Name

4(1H)-Pteridinone, 2-((3-aminopropyl)amino)-6-(1,2-dihydroxypropyl)-, (R-(R*,S*))-

InChi Key

BBFMPNKVCFIPPX-RCOVLWMOSA-N

InChi Code

InChI=1S/C12H18N6O3/c1-6(19)9(20)7-5-15-10-8(16-7)11(21)18-12(17-10)14-4-2-3-13/h5-6,9,19-20H,2-4,13H2,1H3,(H2,14,15,17,18,21)/t6-,9-/m0/s1

SMILES Code

O=C1N=C(NCCCN)NC2=NC=C([C@@H](O)[C@@H](O)C)N=C12

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 294.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Hibiya M, Teradaira R, Shimpo K, Matsui T, Sugimoto T, Nagatsu T. Interference of a methotrexate derivative with urinary oncopterin [N2-(3-aminopropyl)biopterin] measurement by high-performance liquid chromatography with fluorimetric detection. J Chromatogr B Biomed Sci Appl. 1997 Mar 28;691(1):223-7. PubMed PMID: 9140780. 2: Hibiya M, Teradaira R, Sugimoto T, Fujita K, Nagatsu T. Simultaneous determination of N2-(3-aminopropyl)biopterin (oncopterin), biopterin and neopterin by high-performance liquid chromatography with fluorescence detection. J Chromatogr B Biomed Appl. 1995 Oct 6;672(1):143-8. PubMed PMID: 8590927. 3: Ogiwara S, Hidaka H, Sugimoto T, Teradaira R, Fujita K, Nagatsu T. Elevated levels of oncopterin, N2-(3-aminopropyl)biopterin, a new pterin compound, in urine from patients with solid and blood cancers. J Biochem. 1993 Jan;113(1):1-3. PubMed PMID: 8384199. 4: Tomandl J. [Oncopterin in clinical diagnosis]. Vnitr Lek. 1997 Jun;43(6):404-6. Review. Czech. PubMed PMID: 9601874. 5: Shimpo K, Chihara T, Hibiya M, Ito S, Nagatsu T. [Amines and pteridines]. Nihon Rinsho. 1996 Jun;54(6):1515-20. Review. Japanese. PubMed PMID: 8691603.