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MedKoo Cat#: 573351 | Name: Tandamine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tandamine hydrochloride is an antidepressant.

Chemical Structure

Tandamine hydrochloride
Tandamine hydrochloride
CAS#58167-78-5 (HCl)

Theoretical Analysis

MedKoo Cat#: 573351

Name: Tandamine hydrochloride

CAS#: 58167-78-5 (HCl)

Chemical Formula: C18H27ClN2S

Exact Mass: 338.1583

Molecular Weight: 338.94

Elemental Analysis: C, 63.79; H, 8.03; Cl, 10.46; N, 8.27; S, 9.46

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
42408-80-0 (free base) 58167-78-5 (HCl)
Synonym
AY 23946; AY-23,946; Tandamine HCl; Tandamine hydrochloride
IUPAC/Chemical Name
Thiopyrano(3,4-b)indole, 1,3,4,9-tetrahydro-1-dimethylaminoethyl-9-ethyl-1-methyl-, hydrochloride
InChi Key
FJJSKKBQSGDHQK-UHFFFAOYSA-N
InChi Code
1S/C18H26N2S.ClH/c1-5-20-16-9-7-6-8-14(16)15-10-13-21-18(2,17(15)20)11-12-19(3)4;/h6-9H,5,10-13H2,1-4H3;1H
SMILES Code
c1ccc2c3CCS[C@@](c3n(CC)c2c1)(CCN(C)C)C.Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 338.94 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pugsley TA, Lippmann W. Effect of acute and chronic treatment of tandamine, a new heterocyclic antidepressant, on biogenic amine metabolism and related activities. Naunyn Schmiedebergs Arch Pharmacol. 1979 Sep;308(3):239-47. PubMed PMID: 503251. 2: Ehsanullah RS, Ghose K, Kirby MJ, Turner P, Witts D. Clinical pharmacological studies of tandamine, a potential antidepressive drug. Psychopharmacology (Berl). 1977 Mar 23;52(1):73-7. PubMed PMID: 403562. 3: Jirkovsky I, Humber LG, Voith K, Charest MP. Syntheses and primary pharmacological screening of tandamine and related tetrahydrothiopyranoindoles with potential antidepressant properties. Arzneimittelforschung. 1977;27(9):1642-8. PubMed PMID: 579130.

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