Zetomipzomib, also known as KZR-616, is a potent, selective dual immunoproteasome subunit LMP7/LMP2 inhibitor with IC50 of 39 nM/139 nM. KZR-616 is presently in clinical trials for treatment of rheumatic disease.
MedKoo Cat#: 555385
Name: Zetomipzomib
CAS#: 1629677-75-3 (free base)
Chemical Formula: C30H42N4O8
Exact Mass: 586.3003
Molecular Weight: 586.69
Elemental Analysis: C, 61.42; H, 7.22; N, 9.55; O, 21.82
The following data is based on the product molecular weight 586.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
