UF-17 HCl is a selective CXCR4 antagonist that disrupts CXCR4-SDF-1 signaling, crucial for cell migration, immunity, and cancer metastasis. It has potential in oncology, HIV treatment, and stem cell mobilization by reducing tumor progression and enhancing hematopoietic trafficking. UF-17 HCl binds CXCR4 competitively, blocking signaling pathways that drive cell survival, proliferation, and migration.
MedKoo Cat#: 574207
Name: UF-17 HCl
CAS#: NONE
Chemical Formula: C17H27ClN2O
Exact Mass: 310.1812
Molecular Weight: 310.87
Elemental Analysis: C, 65.68; H, 8.75; Cl, 11.40; N, 9.01; O, 5.15
The following data is based on the product molecular weight 310.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |