Aumitin is an autophagy inhibitor, targeting mitochondrial complex I. Macroautophagy is a conserved eukaryotic process for degradation of cellular components in response to lack of nutrients. It is involved in the development of diseases, notably cancer and neurological disorders including Parkinson's disease. Small molecule autophagy modulators have proven to be valuable tools to dissect and interrogate this crucial metabolic pathway and are in high demand.
MedKoo Cat#: 564424
Name: Aumitin
CAS#: 946293-78-3
Chemical Formula: C24H20ClN5O
Exact Mass: 429.1356
Molecular Weight: 429.91
Elemental Analysis: C, 67.05; H, 4.69; Cl, 8.25; N, 16.29; O, 3.72
The following data is based on the product molecular weight 429.91 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
