MedKoo Cat#: 564058 | Name: ZX-J-19L

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZX-J-19L is an inhibitor of Cyclophilin J (CyPJ) PPIase. ZX-J-19L demonstrates remarkable inhibition of tumor cell growth, comparable to CsA but much stronger than 5-fluorouracil.

Chemical Structure

ZX-J-19L
ZX-J-19L
CAS#1346754-06-0

Theoretical Analysis

MedKoo Cat#: 564058

Name: ZX-J-19L

CAS#: 1346754-06-0

Chemical Formula: C24H21N3O

Exact Mass: 367.1685

Molecular Weight: 367.45

Elemental Analysis: C, 78.45; H, 5.76; N, 11.44; O, 4.35

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
ZX-J-19L; ZXJ19L; ZX J 19L; ZXJ-19L; ZX J-19L
IUPAC/Chemical Name
N-(2,3-Diphenylquinoxalin-6-yl)butyramide
InChi Key
ACDUESKKNRCKDL-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H21N3O/c1-2-9-22(28)25-19-14-15-20-21(16-19)27-24(18-12-7-4-8-13-18)23(26-20)17-10-5-3-6-11-17/h3-8,10-16H,2,9H2,1H3,(H,25,28)
SMILES Code
CCCC(NC1=CC=C2N=C(C3=CC=CC=C3)C(C4=CC=CC=C4)=NC2=C1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 367.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhao X, Xia C, Wang X, Wang H, Xin M, Yu L, Liang Y. Cyclophilin J PPIase Inhibitors Derived from 2,3-Quinoxaline-6 Amine Exhibit Antitumor Activity. Front Pharmacol. 2018 Feb 21;9:126. doi: 10.3389/fphar.2018.00126. eCollection 2018. PubMed PMID: 29520233; PubMed Central PMCID: PMC5826973.