Edecesertib, also known as GS-5718, is a serine/threonine kinase inhibitor and anti-inflammatory. Edecesertib can be used for lupus erythematosus (LE) and rheumatoid arthritis (RA) research. Edecesertib (GS-5718) is under development for the treatment of lupus and cutaneous lupus erythematosus (CLE). The drug candidate acts by targeting interleukin-1 receptor-associated kinase 4 (IRAK4). It is administered through oral route.
MedKoo Cat#: 121072
Name: Edecesertib
CAS#: 2408839-73-4
Chemical Formula: C22H22FN7O2
Exact Mass: 435.1819
Molecular Weight: 435.46
Elemental Analysis: C, 60.68; H, 5.09; F, 4.36; N, 22.52; O, 7.35
The following data is based on the product molecular weight 435.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
