MedKoo Cat#: 563912 | Name: Noremopamil

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Noremopamil is a calcium entry blocker, also being used as the precursor for radiolabelling emopamil.

Chemical Structure

Noremopamil
Noremopamil
CAS#86656-29-3 (racemic)

Theoretical Analysis

MedKoo Cat#: 563912

Name: Noremopamil

CAS#: 86656-29-3 (racemic)

Chemical Formula: C22H28N2

Exact Mass: 320.2252

Molecular Weight: 320.48

Elemental Analysis: C, 82.45; H, 8.81; N, 8.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
128194-57-0 (S-isomer) 186763-54-2 (R-isomer) 86656-29-3 (racemic)
Synonym
Noremopamil; Desmethyl emopamil; Desmethyl-emopamil; Desmethylemopamil
IUPAC/Chemical Name
2-Isopropyl-2-phenyl-5-[(2-phenylethyl)amino]pentanenitrile
InChi Key
SWJSQALWXRRRJA-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H28N2/c1-19(2)22(18-23,21-12-7-4-8-13-21)15-9-16-24-17-14-20-10-5-3-6-11-20/h3-8,10-13,19,24H,9,14-17H2,1-2H3
SMILES Code
N#CC(C1=CC=CC=C1)(C(C)C)CCCNCCC2=CC=CC=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 320.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kimura T, Yamamoto N, Suzuki Y, Kawano K, Norimine Y, Ito K, Nagato S, Iimura Y, Yonaga M. Practical synthesis of chiral emopamil left hand as a bioactive motif. J Org Chem. 2002 Aug 23;67(17):6228-31. PubMed PMID: 12182667. 2: Weber J, Bielenberg GW, Krieglstein J. Effects of phenylalkylamine calcium entry blockers on postischemic energy metabolism in the isolated perfused rat brain: stereoselective action of emopamil. Pharmacology. 1988;37(1):38-49. PubMed PMID: 2458606.