MedKoo Cat#: 572667 | Name: BS2G sodium
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BS2G Crosslinker, or Bis[Sulfosuccinimidyl] glutarate), is an amine-reactive, water soluble, homobifunctional protein crosslinker. The BS2G protein crosslinker's 5-atom (7.7 angstrom) spacer arm is non-cleavable and the molecule is not cell membrane permeable. The BS2G crosslinking reagent can be used to label cell surface proteins

Chemical Structure

BS2G sodium
BS2G sodium
CAS#881415-72-1 (sodium)

Theoretical Analysis

MedKoo Cat#: 572667

Name: BS2G sodium

CAS#: 881415-72-1 (sodium)

Chemical Formula: C13H12N2Na2O14S2

Exact Mass: 529.9525

Molecular Weight: 530.34

Elemental Analysis: C, 29.44; H, 2.28; N, 5.28; Na, 8.67; O, 42.23; S, 12.09

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
250mg USD 1,250.00 2 Weeks
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Synonym
BS2G Crosslinker; BS2G Crosslinker sodium;
IUPAC/Chemical Name
sodium 1,1'-(glutaroylbis(oxy))bis(2,5-dioxopyrrolidine-3-sulfonate)
InChi Key
JINCQYPCQMBZSX-UHFFFAOYSA-L
InChi Code
InChI=1S/C13H14N2O14S2.2Na/c16-8-4-6(30(22,23)24)12(20)14(8)28-10(18)2-1-3-11(19)29-15-9(17)5-7(13(15)21)31(25,26)27;;/h6-7H,1-5H2,(H,22,23,24)(H,25,26,27);;/q;2*+1/p-2
SMILES Code
O=C(ON1C(C(S(=O)([O-])=O)CC1=O)=O)CCCC(ON2C(C(S(=O)([O-])=O)CC2=O)=O)=O.[Na+].[Na+]
Appearance
Solid powder
Purity
>90% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 530.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Boni FI, Prezotti FG, Cury BS. Gellan gum microspheres crosslinked with trivalent ion: effect of polymer and crosslinker concentrations on drug release and mucoadhesive properties. Drug Dev Ind Pharm. 2016 Aug;42(8):1283-90. doi: 10.3109/03639045.2015.1125915. Epub 2016 Jan 29. PubMed PMID: 26616390. 2: Van Haute D, Longmate JM, Berlin JM. Controlled Assembly of Biocompatible Metallic Nanoaggregates Using a Small Molecule Crosslinker. Adv Mater. 2015 Sep 16;27(35):5158-64. doi: 10.1002/adma.201501602. Epub 2015 Jul 24. PubMed PMID: 26208123; PubMed Central PMCID: PMC4567412. 3: Rao Z, Sasaki M, Taguchi T. Development of amphiphilic, enzymatically-degradable PEG-peptide conjugate as cell crosslinker for spheroid formation. Colloids Surf B Biointerfaces. 2013 Jan 1;101:223-7. doi: 10.1016/j.colsurfb.2012.06.033. Epub 2012 Jul 4. PubMed PMID: 23010023.