EPZ020411 is a potent and selective PRMT6 inhibitor tool compound. EPZ020411 shows good bioavailability following subcutaneous dosing in rats making it a suitable tool for in vivo studies. EPZ020411 suppresses RCC1 arginine methylation and improves the cytotoxic activity of radiotherapy against GSC brain tumor xenografts.
MedKoo Cat#: 407182
Name: EPZ020411 dihydrochloride
CAS#: 2095432-47-4 (2HCl)
Chemical Formula: C25H40Cl2N4O3
Exact Mass: 442.2944
Molecular Weight: 515.52
Elemental Analysis: C, 58.25; H, 7.82; Cl, 13.75; N, 10.87; O, 9.31
The following data is based on the product molecular weight 515.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
