BTC-8 is a BAX activator, which inhibits GBM cell proliferation, arrests the cell cycle, and induces apoptosis through the induction of mitochondrial membrane permeabilization. BTC-8 is demonstrated to block proliferation and self-renewal of GSCs and induce their apoptosis.
MedKoo Cat#: 563798
Name: BTC-8
CAS#: NONE
Chemical Formula: C26H27N5O3
Exact Mass: 457.2114
Molecular Weight: 457.53
Elemental Analysis: C, 68.25; H, 5.95; N, 15.31; O, 10.49
The following data is based on the product molecular weight 457.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
