Synonym
NOSO-95C; NOSO 95C; NOSO95C;
IUPAC/Chemical Name
(S)-N-((2S,5S,11S,Z)-17-amino-5,11-bis(4-aminobutyl)-8-(3-guanidinopropylidene)-1-(1H-imidazol-5-yl)-3,6,9,12-tetraoxo-4,7,10,13-tetraazaheptadecan-2-yl)-1-((2R,8S,11S,14S)-14,18-diamino-8,11-bis((S)-2-amino-1-hydroxyethyl)-2-(3-aminopropyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazaoctadecanoyl)pyrrolidine-2-carboxamide
InChi Key
VFODIGMPMDOVDF-SLXJRBCYSA-N
InChi Code
InChI=1S/C54H101N23O12/c55-18-4-1-12-33(62)45(81)75-44(41(79)28-61)52(88)76-43(40(78)27-60)51(87)68-30-42(80)70-37(15-9-22-59)53(89)77-25-11-17-39(77)50(86)74-38(26-32-29-65-31-69-32)49(85)73-35(14-3-6-20-57)47(83)72-36(16-10-24-67-54(63)64)48(84)71-34(13-2-5-19-56)46(82)66-23-8-7-21-58/h16,29,31,33-35,37-41,43-44,78-79H,1-15,17-28,30,55-62H2,(H,65,69)(H,66,82)(H,68,87)(H,70,80)(H,71,84)(H,72,83)(H,73,85)(H,74,86)(H,75,81)(H,76,88)(H4,63,64,67)/b36-16-/t33-,34-,35-,37+,38-,39-,40-,41-,43-,44-/m0/s1
SMILES Code
O=C([C@H]1N(C([C@@H](CCCN)NC(CNC([C@@H](NC([C@@H](NC([C@H](CCCCN)N)=O)[C@H](CN)O)=O)[C@H](CN)O)=O)=O)=O)CCC1)N[C@H](C(N[C@@H](CCCCN)C(N/C(C(N[C@@H](CCCCN)C(NCCCCN)=O)=O)=C\CCNC(N)=N)=O)=O)CC2=CN=CN2
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
NOSO-95C is a 10-mer linear cationic peptide containing six proteinogenic and four nonstandard amino acids: ((2S,3S)-α,γ-diamino β-hydroxy butyric acid (Dab(βOH)) in positions 2 and 3, Dornithine (D-Orn) in position 5, Z-α,β−dehydroarginine (Dha) in position 9, and a functionalized secondary amide at the Cterminal position (α,δ−diamino butane (Dbt)).
