MedKoo Cat#: 574614 | Name: CAY10681
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CAY10681 is a dual modulator of p53-MDM2 interaction and NF-κB signaling.

Chemical Structure

CAY10681
CAY10681
CAS#1542066-69-2

Theoretical Analysis

MedKoo Cat#: 574614

Name: CAY10681

CAS#: 1542066-69-2

Chemical Formula: C30H26BrN5O

Exact Mass: 551.1321

Molecular Weight: 552.48

Elemental Analysis: C, 65.22; H, 4.74; Br, 14.46; N, 12.68; O, 2.90

Price and Availability

Size Price Availability Quantity
1mg USD 285.00 2 Weeks
5mg USD 705.00 2 Weeks
10mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
CAY 10681, CAY-10681, CAY10681
IUPAC/Chemical Name
4-(4-bromophenyl)-4,5-dihydro-5-[3-(1H-imidazol-1-yl)propyl]-3-phenyl-1-(phenylmethyl)-pyrrolo[3,4-c]pyrazol-6(1H)-one
InChi Key
HZXBRCFEDOCBBP-UHFFFAOYSA-N
InChi Code
InChI=1S/C30H26BrN5O/c31-25-14-12-24(13-15-25)28-26-27(23-10-5-2-6-11-23)33-36(20-22-8-3-1-4-9-22)29(26)30(37)35(28)18-7-17-34-19-16-32-21-34/h1-6,8-16,19,21,28H,7,17-18,20H2
SMILES Code
O=C1N(CCCN2C=CN=C2)C(C3=CC=C(Br)C=C3)C4=C1N(CC5=CC=CC=C5)N=C4C6=CC=CC=C6
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 552.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Zhuang, C., Miao, Z., Wu, Y., et al. Double-edged swords as cancer therapeutics: Novel, orally active, small molecules simultaneously inhibit p53-MDM2 interaction and the NF-κB pathway. Journal of Medicinal Chemistry 57(3), 567-577 (2014).