Tecalcet Free Base | CAS# 148717-54-8 (free base) | oral calcium receptor agonist

MedKoo Cat#: 414513 | Name: Tecalcet Free Base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tecalcet Free Base is an oral calcium receptor agonist

Chemical Structure

Tecalcet Free Base

CAS#148717-54-8 (free base)

Theoretical Analysis

MedKoo Cat#: 414513

Name: Tecalcet Free Base

CAS#: 148717-54-8 (free base)

Chemical Formula: C18H22ClNO

Exact Mass: 303.1390

Molecular Weight: 303.83

Elemental Analysis: C, 71.16; H, 7.30; Cl, 11.67; N, 4.61; O, 5.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

148717-54-8 (free base); 177172-49-5 (HCl)

Synonym

Tecalcet Free Base; R568; R-568; R 568

IUPAC/Chemical Name

Benzenepropanamine, 2-chloro-N-(1-(3-methoxyphenyl)ethyl)-, (R)-

InChi Key

ZVQUCWXZCKWZBP-CQSZACIVSA-N

InChi Code

InChI=1S/C18H22ClNO/c1-14(16-8-5-10-17(13-16)21-2)20-12-6-9-15-7-3-4-11-18(15)19/h3-5,7-8,10-11,13-14,20H,6,9,12H2,1-2H3/t14-/m1/s1

SMILES Code

C[C@@H](NCCCC1=CC=CC=C1Cl)C2=CC=CC(OC)=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 303.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Iqbal J, Zaidi M, Schneider AE. Cinacalcet hydrochloride (Amgen). IDrugs. 2003 Jun;6(6):587-92. PMID: 12811682. 2: Blasius CK, Heinrich NF, Vasilenko V, Gade LH. Tackling N-Alkyl Imines with 3d Metal Catalysis: Highly Enantioselective Iron-Catalyzed Synthesis of α-Chiral Amines. Angew Chem Int Ed Engl. 2020 Sep 7;59(37):15974-15977. doi: 10.1002/anie.202006557. Epub 2020 Jun 25. PMID: 32453491; PMCID: PMC7539954. 3: Cinacalcet: AMG 073, Calcimimetics--Amgen/NPS Pharmaceuticals, KRN 1493, NPS 1493. Drugs R D. 2003;4(6):349-51. doi: 10.2165/00126839-200304060-00003. PMID: 14584963.