Propionylmaridomycin | CAS#35775-65-6 | macrolide antibiotic

MedKoo Cat#: 598662 | Name: Propionylmaridomycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Propionylmaridomycin is a macrolide antibiotic.

Chemical Structure

Propionylmaridomycin

CAS#35775-65-6

Theoretical Analysis

MedKoo Cat#: 598662

Name: Propionylmaridomycin

CAS#: 35775-65-6

Chemical Formula: C46H75NO17

Exact Mass: 913.5035

Molecular Weight: 914.09

Elemental Analysis: C, 60.44; H, 8.27; N, 1.53; O, 29.75

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Propionylmaridomycin; Propionylmaridomycin I;

IUPAC/Chemical Name

(1R,3R,7R,8R,9S,10R,12R,13S,16R,E)-9-(((2R,3S,4S,5R,6R)-4-(dimethylamino)-3-hydroxy-5-(((2S,4S,5S,6S)-4-hydroxy-4,6-dimethyl-5-((3-methylbutanoyl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-methoxy-3,12-dimethyl-5-oxo-10-(2-oxoethyl)-4,17-dioxabicyclo[14.1.0]heptadec-14-ene-7,13-diyl dipropionate

InChi Key

YOEZGCFEDPFSHG-IHBICIFHSA-N

InChi Code

InChI=1S/C46H75NO17/c1-13-34(49)60-30-15-16-31-32(59-31)21-26(6)56-37(52)22-33(61-35(50)14-2)43(55-12)42(29(17-18-48)20-25(30)5)64-45-40(53)39(47(10)11)41(27(7)58-45)63-38-23-46(9,54)44(28(8)57-38)62-36(51)19-24(3)4/h15-16,18,24-33,38-45,53-54H,13-14,17,19-23H2,1-12H3/b16-15+/t25-,26-,27-,28+,29+,30-,31-,32-,33-,38+,39+,40+,41+,42+,43-,44+,45-,46+/m1/s1

SMILES Code

C[C@@H]([C@H](OC(CC(C)C)=O)[C@@](C)(O)C1)O[C@H]1O[C@@H]2[C@H]([C@H](O)[C@H](O[C@@H]2C)O[C@@H]3[C@H](OC)[C@H](OC(CC)=O)CC(O[C@H](C)C[C@@H]4[C@H](O4)/C=C/[C@H]([C@H](C)C[C@@H]3CC=O)OC(CC)=O)=O)N(C)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 914.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Matsuzawa T, Kondo T, Kita Y. Studies on the absorption, distribution, metabolism, and excretion of propionylmaridomycin in rats. Antimicrob Agents Chemother. 1974 Dec;6(6):685-90. PubMed PMID: 4451342; PubMed Central PMCID: PMC444720. 2: Kondo M, Oishi T, Tsuchiya K, Goto S, Kuwahara S. Maridomycin, a new macrolide antibiotic. In vitro antibacterial activity of 9-propionylmaridomycin. Antimicrob Agents Chemother. 1973 Aug;4(2):149-55. PubMed PMID: 4790935; PubMed Central PMCID: PMC444520. 3: Kondo M, Ishifuji K, Tsuchiya K, Goto S, Kuwahara S. Maridomycin, a new macrolide antibiotic: in vivo antibacterial activity of 9-propionylmaridomycin. Antimicrob Agents Chemother. 1973 Aug;4(2):156-9. PubMed PMID: 4790936; PubMed Central PMCID: PMC444521. 4: Katsu M, Fujimoro I, Shimada S, Fujii T, Matsumoto K. [Effect of propionylmaridomycin in respiratory infections - a double blind study]. Kansenshogaku Zasshi. 1974 Sep;48(9):357-68. Japanese. PubMed PMID: 4218863. 5: Kunishige N, Kawamura K, Muroi M, Kishi T. Maridomycin, a new macrolide antibiotic. XII. A simple quantitative analysis of 9-propionylmaridomycin components. Chem Pharm Bull (Tokyo). 1975 Dec;23(12):3075-80. PubMed PMID: 1218448. 6: Muroi M, Izawa M, Kishi T. Maridomycin, a new macrolide antibiotic. 8. Isolation and structures of metabolites of 9-propionylmaridomycin. J Antibiot (Tokyo). 1974 Jun;27(6):449-59. PubMed PMID: 4853097. 7: Ono H, Harada S, Kishi T. Maridomycin, a new macrolide antibiotic. VII. Incorporation of labeled precursors into maridomycin and preparation of 14C-labeled 9-propionylmaridomycin. J Antibiot (Tokyo). 1974 Jun;27(6):442-8. PubMed PMID: 4853096. 8: Harada S, Muroi M, Kondo M, Tsuchiya K, Matsuzawa T. Chemical modification of maridomycin, a new macrolide antibiotic. Antimicrob Agents Chemother. 1973 Aug;4(2):140-8. PubMed PMID: 4790934; PubMed Central PMCID: PMC444519. 9: Kondo K. Analytical studies of maridomycin. II. Separation of 9-propionylmaridomycins by thin-layer chromatography. J Chromatogr. 1979 Feb 1;169:337-42. PubMed PMID: 536424.