Propoxur | CAS#114-26-1 | Insecticide

MedKoo Cat#: 526061 | Name: Propoxur

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Propoxur is a carbamate insecticide. Propoxur is a non-systemic insecticide with a fast knockdown and long residual effect used against turf, forestry, and household pests and fleas.

Chemical Structure

Propoxur

CAS#114-26-1

Theoretical Analysis

MedKoo Cat#: 526061

Name: Propoxur

CAS#: 114-26-1

Chemical Formula: C11H15NO3

Exact Mass: 209.1052

Molecular Weight: 209.25

Elemental Analysis: C, 63.14; H, 7.23; N, 6.69; O, 22.94

Price and Availability

Size	Price	Availability	Quantity
1g	USD 350.00
10g	USD 1,450.00

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Related CAS #

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Synonym

Propoxur; Baygon; AI3-25671; Aprocarb; Arprocarb; BAY 39007; BAY 5122; Isocarb; Mrowkozol; NSC 379584; Propoxylor; Propyon; Rhoden.

IUPAC/Chemical Name

2-(1-Methylethoxy)phenol methylcarbamate

InChi Key

ISRUGXGCCGIOQO-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H15NO3/c1-8(2)14-9-6-4-5-7-10(9)15-11(13)12-3/h4-8H,1-3H3,(H,12,13)

SMILES Code

CC(C)OC1=CC=CC=C1OC(NC)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Other names: Arprocarb; Bayer 39007; Bayer B 5122; Baygon G; Blattanex; Blattosep; Bolfo; Boruho; Boruho 50; Brygou; Dalf Dust; ENT 25,671; IPMC; Invisi-Gard; Mrowkozol; NSC 379584; O-(2-Isopropoxyphenyl) N-methylcarbamate; OMS 33; PHC 7; Propotox; Propoxylor; Sendran; Suncide; Tendex;

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 209.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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The urinary bladder carcinogen propoxur does not produce genotoxic effects in the urinary bladder of Wistar male rats. Exp Toxicol Pathol. 2015 Sep;67(9):453-8. doi: 10.1016/j.etp.2015.06.002. Epub 2015 Jul 8. PubMed PMID: 26164753. 5: Yazdian S, Fahham N, Ghahremani MH, Afzali M, Farsandaj N, Vatankhah M, Ostad SN. Evaluation of the expression of P-glycoprotein in propoxur-resistant Caco-2 cells. Acta Med Iran. 2014;52(10):728-33. PubMed PMID: 25369005. 6: Khodadoust S, Talebianpoor MS, Ghaedi M. Application of an optimized dispersive nanomaterial ultrasound-assisted microextraction method for preconcentration of carbofuran and propoxur and their determination by high-performance liquid chromatography with UV detection. J Sep Sci. 2014 Nov;37(21):3117-24. doi: 10.1002/jssc.201400816. Epub 2014 Sep 18. PubMed PMID: 25234016. 7: Santa-Cruz P, García-Reiriz A. Application of third-order multivariate calibration algorithms to the determination of carbaryl, naphthol and propoxur by kinetic spectroscopic measurements. Talanta. 2014 Oct;128:450-9. doi: 10.1016/j.talanta.2014.04.075. Epub 2014 May 6. PubMed PMID: 25059185. 8: Akıner MM. [Malathion and propoxur resistance in Turkish populations of the Anopheles maculipennis Meigen (Diptera: Culicidae) and relation to the insensitive acetylcholinesterase]. Turkiye Parazitol Derg. 2014 Jun;38(2):111-5. doi: 10.5152/tpd.2014.3388. Turkish. PubMed PMID: 25016118. 9: Zafiropoulos A, Tsarouhas K, Tsitsimpikou C, Fragkiadaki P, Germanakis I, Tsardi M, Maravgakis G, Goutzourelas N, Vasilaki F, Kouretas D, Hayes A, Tsatsakis A. Cardiotoxicity in rabbits after a low-level exposure to diazinon, propoxur, and chlorpyrifos. Hum Exp Toxicol. 2014 Dec;33(12):1241-52. doi: 10.1177/0960327114532384. Epub 2014 May 12. PubMed PMID: 24818614. 10: Mehta KD, Mehta AK, Halder S, Khanna N, Tripathi AK, Sharma KK. Protective effect of melatonin on propoxur-induced impairment of memory and oxidative stress in rats. Environ Toxicol. 2014 Jun;29(6):705-13. doi: 10.1002/tox.21798. Epub 2012 Jul 30. PubMed PMID: 24733834. 11: Ostrea EM Jr, Villanueva-Uy E, Bielawski D, Birn S, Janisse JJ. Trends in long term exposure to propoxur and pyrethroids in young children in the Philippines. Environ Res. 2014 May;131:13-6. doi: 10.1016/j.envres.2014.01.003. Epub 2014 Mar 15. PubMed PMID: 24637179. 12: Pandey MR, Guo H. Evaluation of cytotoxicity, genotoxicity and embryotoxicity of insecticide propoxur using flounder gill (FG) cells and zebrafish embryos. Toxicol In Vitro. 2014 Apr;28(3):340-53. doi: 10.1016/j.tiv.2013.11.010. Epub 2013 Nov 28. PubMed PMID: 24291161. 13: Kumar S, Mahajan G, Walia V, Kumar N. Baygon (Propoxur) poisoning leading to acute respiratory distress syndrome (ARDS). Indian J Pediatr. 2014 Jul;81(7):730-1. doi: 10.1007/s12098-013-1240-3. Epub 2013 Sep 26. PubMed PMID: 24068625. 14: Low VL, Chen CD, Lee HL, Lim PE, Leong CS, Sofian-Azirun M. Current susceptibility status of Malaysian Culex quinquefasciatus (Diptera: Culicidae) against DDT, propoxur, malathion, and permethrin. J Med Entomol. 2013 Jan;50(1):103-11. PubMed PMID: 23427658. 15: Liang YJ, Wang HP, Long DX, Wu YJ. Applying biofluid metabonomic techniques to analyze the combined subchronic toxicity of propoxur and permethrin in rats. Bioanalysis. 2012 Dec;4(24):2897-907. doi: 10.4155/bio.12.277. PubMed PMID: 23244281. 16: Tsitsimpikou C, Tzatzarakis M, Fragkiadaki P, Kovatsi L, Stivaktakis P, Kalogeraki A, Kouretas D, Tsatsakis AM. Histopathological lesions, oxidative stress and genotoxic effects in liver and kidneys following long term exposure of rabbits to diazinon and propoxur. Toxicology. 2013 May 10;307:109-14. doi: 10.1016/j.tox.2012.11.002. Epub 2012 Nov 28. PubMed PMID: 23201499. 17: Liang YJ, Wang HP, Long DX, Wu YJ. (1)H NMR-based metabonomic profiling of rat serum and urine to characterize the subacute effects of carbamate insecticide propoxur. Biomarkers. 2012 Sep;17(6):566-74. doi: 10.3109/1354750X.2012.704527. Epub 2012 Jul 10. PubMed PMID: 22780197. 18: Gül A, Benli AÇ, Ayhan A, Memmi BK, Selvi M, Sepici-Dinçel A, Cakiroğullari GÇ, Erkoç F. Sublethal propoxur toxicity to juvenile common carp (Cyprinus carpio L., 1758): biochemical, hematological, histopathological, and genotoxicity effects. Environ Toxicol Chem. 2012 Sep;31(9):2085-92. doi: 10.1002/etc.1924. Epub 2012 Aug 1. PubMed PMID: 22730006. 19: Liang YJ, Wang HP, Yang L, Li W, Wu YJ. Metabonomic responses in rat urine following subacute exposure to propoxur. Int J Toxicol. 2012 Jun;31(3):287-93. doi: 10.1177/1091581812441030. Epub 2012 May 1. PubMed PMID: 22550049. 20: Kovacic P, Somanathan R. Propoxur: a novel mechanism for insecticidal action and toxicity. Rev Environ Contam Toxicol. 2012;218:141-50. doi: 10.1007/978-1-4614-3137-4_4. Review. PubMed PMID: 22488607.