MedKoo Cat#: 598598 | Name: Leptodactyline

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Leptodactyline is a naturally occurring quaternary ammonium base.

Chemical Structure

Leptodactyline
Leptodactyline
CAS#13957-33-0

Theoretical Analysis

MedKoo Cat#: 598598

Name: Leptodactyline

CAS#: 13957-33-0

Chemical Formula: C11H18NO

Exact Mass: 180.1383

Molecular Weight: 180.27

Elemental Analysis: C, 73.29; H, 10.06; N, 7.77; O, 8.87

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Leptodactyline;
IUPAC/Chemical Name
2-(3-hydroxyphenyl)-N,N,N-trimethylethan-1-aminium
InChi Key
VLDBEZDOSUKOBS-UHFFFAOYSA-O
InChi Code
InChI=1S/C11H17NO/c1-12(2,3)8-7-10-5-4-6-11(13)9-10/h4-6,9H,7-8H2,1-3H3/p+1
SMILES Code
C[N+](C)(C)CCC1=CC=CC(O)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 180.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pereira EB, Collevatti RG, Kokubum MN, Miranda NE, Maciel NM. Ancestral reconstruction of reproductive traits shows no tendency toward terrestriality in leptodactyline frogs. BMC Evol Biol. 2015 May 20;15:91. doi: 10.1186/s12862-015-0365-6. PubMed PMID: 25987435; PubMed Central PMCID: PMC4437749. 2: ERSPAMER V, GLASSER A. The pharmacological actions of (m-hydroxyphenethyl) trimethylammonium (leptodactyline). Br J Pharmacol Chemother. 1960 Mar;15:14-22. PubMed PMID: 13820718; PubMed Central PMCID: PMC1481971. 3: ERSPAMER V. [Not Available]. Arch Biochem Biophys. 1959 Jun;82(2):431-8. PubMed PMID: 13661968. 4: Roseghini M, Erspamer V, Falconieri Erspamer G, Cei JM. Indole-, imidazole- and phenyl-alkylamines in the skin of one hundred and forty American amphibian species other than bufonids. Comp Biochem Physiol C. 1986;85(1):139-47. PubMed PMID: 2877780.