MedKoo Cat#: 413515 | Name: Delucemine Free Base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Delucemine Free Base is an NMDA Receptor Antagonist

Chemical Structure

Delucemine Free Base
Delucemine Free Base
CAS#186495-49-8 (free base)

Theoretical Analysis

MedKoo Cat#: 413515

Name: Delucemine Free Base

CAS#: 186495-49-8 (free base)

Chemical Formula: C16H17F2N

Exact Mass: 261.1329

Molecular Weight: 261.31

Elemental Analysis: C, 73.54; H, 6.56; F, 14.54; N, 5.36

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Delucemine Free Base; NPS1506; NPS-1506; NPS 1506
IUPAC/Chemical Name
3,3-Bis(3-fluorophenyl)-N-methylpropan-1-amine
InChi Key
MUGNLPWYHGOJEG-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H17F2N/c1-19-9-8-16(12-4-2-6-14(17)10-12)13-5-3-7-15(18)11-13/h2-7,10-11,16,19H,8-9H2,1H3
SMILES Code
CNCCC(C1=CC=CC(F)=C1)C2=CC=CC(F)=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
To be determined 0.0 0.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 261.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Browne KD, Leoni MJ, Iwata A, Chen XH, Smith DH. Acute treatment with MgSO4 attenuates long-term hippocampal tissue loss after brain trauma in the rat. J Neurosci Res. 2004 Sep 15;77(6):878-83. PubMed PMID: 15334605. 2: Fuchigami T, Haradahira T, Arai T, Okauchi T, Maeda J, Suzuki K, Yamamoto F, Suhara T, Sasaki S, Maeda M. Synthesis and brain regional distribution of [11C]NPS 1506 in mice and rat: an N-methyl-D-aspartate (NMDA) receptor antagonist. Biol Pharm Bull. 2003 Nov;26(11):1570-3. PubMed PMID: 14600403. 3: Lorber A, Artru AA, Lam MA, Mueller LA, Karpas Z, Roytblat L, Shapira Y. NPS 1506: a novel NMDA receptor antagonist: neuroprotective effects in a model of closed head trauma in rats. J Neurosurg Anesthesiol. 2000 Oct;12(4):345-55. PubMed PMID: 11147383. 4: Leoni MJ, Chen XH, Mueller AL, Cheney J, McIntosh TK, Smith DH. NPS 1506 attenuates cognitive dysfunction and hippocampal neuron death following brain trauma in the rat. Exp Neurol. 2000 Dec;166(2):442-9. PubMed PMID: 11085909. 5: Mueller AL, Artman LD, Balandrin MF, Brady E, Chien Y, DelMar EG, Kierstead A, Marriott TB, Moe ST, Raszkiewicz JL, VanWagenen B, Wells D. NPS 1506, a moderate affinity uncompetitive NMDA receptor antagonist: preclinical summary and clinical experience. Amino Acids. 2000;19(1):177-9. PubMed PMID: 11026487. 6: Mueller AL, Artman LD, Balandrin MF, Brady E, Chien Y, Delmar EG, George K, Kierstead A, Marriott TB, Moe ST, Newman MK, Raszkiewicz JL, Sanguinetti EL, van Wagenen BC, Wells D. NPS 1506, a novel NMDA receptor antagonist and neuroprotectant. Review of preclinical and clinical studies. Ann N Y Acad Sci. 1999;890:450-7. Review. PubMed PMID: 10668449.