Delucemine Hydrochloride, also known as NPS-1506, is a glutamate receptor antagonist potentially for the treatment of major depressive disorder and stroke. Delucemine Hydrochloride is a moderate affinity antagonist that inhibits NMDA/glycine-induced increases in cytosolic calcium in cultured rat cerebellar granule cells and displaces the binding of [3H]MK-801 to rat cortical membranes. Delucemine Hydrochloride improved measures of brain tissue edema and ion homeostasis.
MedKoo Cat#: 528314
Name: Delucemine Hydrochloride
CAS#: 186495-99-8 (HCl)
Chemical Formula: C16H18ClF2N
Exact Mass:
Molecular Weight: 297.77
Elemental Analysis: C, 64.54; H, 6.09; Cl, 11.91; F, 12.76; N, 4.70
The following data is based on the product molecular weight 297.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
