Bamethan sulfate | CAS#5716-20-1 | Vasodilator

MedKoo Cat#: 592553 | Name: Bamethan sulfate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bamethan sulfate is a Vasodilator.

Chemical Structure

Bamethan sulfate

CAS#5716-20-1 (sulfate)

Theoretical Analysis

MedKoo Cat#: 592553

Name: Bamethan sulfate

CAS#: 5716-20-1 (sulfate)

Chemical Formula: C24H40N2O8S

Exact Mass: 516.2505

Molecular Weight: 516.65

Elemental Analysis: C, 55.79; H, 7.80; N, 5.42; O, 24.77; S, 6.21

Price and Availability

Size	Price	Availability	Quantity

Bulk Inquiry

Buy Now

Add to Cart

Related CAS #

3703-79-5 (free base) 5716-20-1 (sulfate)

Synonym

Bamethan sulfate; Bametan sulfate; Bascurat; Bupatol; Butedrin;Butibatol; Periphetol; Rotesar; Vasculat; Vasculit;Vaskulat;

IUPAC/Chemical Name

Benzenemethanol, alpha-((butylamino)methyl)-4-hydroxy-, sulfate (2:1) (salt)

InChi Key

PARMADWNFXEEFC-UHFFFAOYSA-N

InChi Code

InChI=1S/2C12H19NO2.H2O4S/c2*1-2-3-8-13-9-12(15)10-4-6-11(14)7-5-10;1-5(2,3)4/h2*4-7,12-15H,2-3,8-9H2,1H3;(H2,1,2,3,4)

SMILES Code

OC(CNCCCC)C1=CC=C(O)C=C1.OC(CNCCCC)C2=CC=C(O)C=C2.O=S(O)(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 516.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Li T, Cao J, Li Z, Wang X, He P. Broad screening and identification of β-agonists in feed and animal body fluid and tissues using ultra-high performance liquid chromatography-quadrupole-orbitrap high resolution mass spectrometry combined with spectra library search. Food Chem. 2016 Feb 1;192:188-96. doi: 10.1016/j.foodchem.2015.06.104. Epub 2015 Jun 30. PubMed PMID: 26304337. 2: Deng Y, Zhang H, Wu JT, Olah TV. Tandem mass spectrometry with online high-flow reversed-phase extraction and normal-phase chromatography on silica columns with aqueous-organic mobile phase for quantitation of polar compounds in biological fluids. Rapid Commun Mass Spectrom. 2005;19(20):2929-34. PubMed PMID: 16175657. 3: Shou WZ, Bu HZ, Addison T, Jiang X, Naidong W. Development and validation of a liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the determination of ribavirin in human plasma and serum. J Pharm Biomed Anal. 2002 Jun 20;29(1-2):83-94. PubMed PMID: 12062668. 4: Loss JR 2nd, Orzechowski RF, Hock RS. Measurement of albuterol in guinea pig serum by high performance liquid chromatography with fluorescence detection. Biomed Chromatogr. 2000 Feb;14(1):1-5. PubMed PMID: 10664547. 5: Schmid MG, Laffranchini M, Dreveny D, Gübitz G. Chiral separation of sympathomimetics by ligand exchange capillary electrophoresis. Electrophoresis. 1999 Sep;20(12):2458-61. PubMed PMID: 10499338. 6: Brambilla G, Fiori M, Curiel I, Serpe L, Gallo P. Alpha 1-acid glycoprotein affinity columns for the clean-up of adrenergic drugs. Analyst. 1998 Dec;123(12):2693-6. PubMed PMID: 10435325. 7: Armstrong DW, Rundlett K, Reid GL 3rd. Use of a macrocyclic antibiotic, rifamycin B, and indirect detection for the resolution of racemic amino alcohols by CE. Anal Chem. 1994 May 15;66(10):1690-5. PubMed PMID: 8030783. 8: Gupta RN, Fuller HD, Dolovich MB. Optimization of a column liquid chromatographic procedure for the determination of plasma salbutamol concentration. J Chromatogr B Biomed Appl. 1994 Apr 1;654(2):205-11. PubMed PMID: 8044281. 9: Kato T, Kikugawa K. Proteins and amino acids as scavengers of nitrite: inhibitory effect on the formation of nitrosodimethylamine and diazoquinone. Food Chem Toxicol. 1992 Jul;30(7):617-26. PubMed PMID: 1521836. 10: Kotwica J, Skarzyński D, Jaroszewski J. Involvement of beta-adrenoceptors in the regulation of luteal function in cattle. Br Vet J. 1991 May-Jun;147(3):189-96. PubMed PMID: 1652346. 11: Miller RB. A validated high-performance liquid chromatographic method for the determination of atenolol in whole blood. J Pharm Biomed Anal. 1991;9(10-12):849-53. PubMed PMID: 1822203. 12: Furihata C, Yamakoshi A, Matsushima T, Kato T, Kikugawa K. Possible tumour-initiating and -promoting activities of 3-diazo-N-nitrosobamethan in rat stomach mucosa. Mutagenesis. 1988 Jul;3(4):299-301. PubMed PMID: 2905413. 13: Kikugawa K, Kato T, Takeda Y. Formation of a highly mutagenic diazo compound from the bamethan-nitrite reaction. Mutat Res. 1987 Mar;177(1):35-43. PubMed PMID: 2881202. 14: Koster AS, Frankhuijzen-Sierevogel AC, Noordhoek J. Glucuronidation of morphine and six beta 2-sympathomimetics in isolated rat intestinal epithelial cells. Drug Metab Dispos. 1985 Mar-Apr;13(2):232-8. PubMed PMID: 2859174. 15: Pugliese R, Sportelli P, Sabato O, Stella M, Nazzaro P, Izzo P. [Bamethan therapy in chronic vascular insufficiency of the inferior arteries]. Clin Ter. 1982 Sep 30;102(6):599-605. Italian. PubMed PMID: 6128098. 16: Giaretti R, Astengo F, Astengo D, Coviello L, Fuliano P, Giaretti G, Melga P. [Effects of a bamethan-inositol nicotinate combination on psycho-organic disease in the elderly]. Clin Ter. 1982 Jan 31;100(2):157-65. Italian. PubMed PMID: 6137308. 17: Corti P, Sciarra G. [Use of derivative resolution for the spectrophotometric analysis of drug mixtures. I. Determination of inositol hexanicotinate and bamethan sulfate in tablets]. Boll Chim Farm. 1981 Nov;120(11):657-67. Italian. PubMed PMID: 6122456. 18: Mottolese C, Cerillo A, Falivene R, Vizioli L, Donati PA. Neri-Barré-Lieou syndrome. Nosographical arrangement and bamethan therapy results. J Neurosurg Sci. 1981 Jul-Dec;25(3-4):173-8. PubMed PMID: 6125575. 19: Cucinotta D, Silvestrini C, Mancini M, Maini C, Passeri M. [Experience with the medical treatment of chronic cerebrovascular insufficiency: bamethan and inositol nicotinate versus placebo]. G Clin Med. 1981 May;62(5):339-50. Italian. PubMed PMID: 6115790. 20: Hengstmann JH, Steinkamp B. [Pharmacokinetics of 3H-bamethan in humans]. Arzneimittelforschung. 1981;31(5):843-8. German. PubMed PMID: 6115653.