Cycloxydim | CAS#101205-02-1 | cyclohexene oxime herbicide

MedKoo Cat#: 598417 | Name: Cycloxydim

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Cycloxydim is a selective post-emergence herbicide belonging to the cyclohexanedione (DIM) chemical class, used primarily for controlling grass weeds in broadleaf crops such as soybeans, sugar beets, and canola. Its mechanism of action involves inhibition of acetyl-CoA carboxylase (ACCase), an essential enzyme in fatty acid biosynthesis in grasses, leading to disrupted membrane formation and plant death. Cycloxydim is rapidly absorbed by foliage and translocated to meristematic tissues, providing effective and targeted grass control without harming dicot crops.

Chemical Structure

Cycloxydim

CAS#101205-02-1

Theoretical Analysis

MedKoo Cat#: 598417

Name: Cycloxydim

CAS#: 101205-02-1

Chemical Formula: C17H27NO3S

Exact Mass: 325.1712

Molecular Weight: 325.46

Elemental Analysis: C, 62.74; H, 8.36; N, 4.30; O, 14.75; S, 9.85

Price and Availability

Size	Price	Availability	Quantity
100mg	USD 350.00	2 Weeks

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Synonym

Cycloxydim; Cycloxidim; Cycloxydime; Focus Ultra; BAS 517-02H; BAS-517-02H; BAS517-02H; BAS 517H; BAS-517H; BAS517H;

IUPAC/Chemical Name

(Z)-2-(1-(ethoxyimino)butyl)-3-hydroxy-5-(tetrahydro-2H-thiopyran-3-yl)cyclohex-2-en-1-one

InChi Key

GGWHBJGBERXSLL-JXAWBTAJSA-N

InChi Code

InChI=1S/C17H27NO3S/c1-3-6-14(18-21-4-2)17-15(19)9-13(10-16(17)20)12-7-5-8-22-11-12/h12-13,19H,3-11H2,1-2H3/b18-14-

SMILES Code

O=C1C(/C(CCC)=N\OCC)=C(O)CC(C2CSCCC2)C1

Appearance

Solid powder

Purity

>95% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 325.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Papapanagiotou AP, Alvanou MV, Giantsis IA, Vasilakoglou I, Eleftherohorinos IG. Characterization of the Giant Foxtail's (Setaria faberi) ALS Gene and Its Enhanced Metabolism-Based Cross-Resistance to Nicosulfuron and Rimsulfuron. Genes (Basel). 2025 Apr 27;16(5):505. doi: 10.3390/genes16050505. PMID: 40428327; PMCID: PMC12111008. 2: Kravos A, Cristaudo F, Bello FD, Medana C, Prosen H, Calza P. Insight into photocatalyzed transformations of multiclass organic contaminants in water. J Chromatogr A. 2025 Jul 5;1752:465971. doi: 10.1016/j.chroma.2025.465971. Epub 2025 Apr 16. PMID: 40273567. 3: Vijayarajan VBA, Torra J, Runge F, de Jong H, van de Belt J, Hennessy M, Forristal PD. Confirmation and characterisation of ALS inhibitor resistant Poa trivialis from Ireland. Pestic Biochem Physiol. 2025 Mar;208:106266. doi: 10.1016/j.pestbp.2024.106266. Epub 2024 Dec 20. PMID: 40015858. 4: European Food Safety Authority (EFSA); Bellisai G, Bernasconi G, Cabrera LC, Castellan I, Del Aguila M, Ferreira L, Greco L, Jarrah S, Leuschner R, Mioč A, Nave S, Reich H, Ruocco S, Scarlato AP, Szot M, Theobald A, Tiramani M, Verani A. Modification of the existing maximum residue levels for cycloxydim in various crops. EFSA J. 2024 Sep 17;22(9):e8996. doi: 10.2903/j.efsa.2024.8996. PMID: 39290980; PMCID: PMC11406146. 5: Kruisdijk E, Zietzschmann F, Stuyfzand PJ, van Breukelen BM. Intra aquifer variations in pesticide sorption during a field injection experiment. J Contam Hydrol. 2022 Jun;248:104015. doi: 10.1016/j.jconhyd.2022.104015. Epub 2022 Apr 26. PMID: 35489141. 6: Lafay F, Daniele G, Fieu M, Pelosi C, Fritsch C, Vulliet E. Ultrasound- assisted QuEChERS-based extraction using EDTA for determination of currently- used pesticides at trace levels in soil. Environ Sci Pollut Res Int. 2022 Mar 3. doi: 10.1007/s11356-022-19397-3. Epub ahead of print. PMID: 35239121. 7: Kaundun SS, Downes J, Jackson LV, Hutchings SJ, Mcindoe E. Impact of a Novel W2027L Mutation and Non-Target Site Resistance on Acetyl-CoA Carboxylase- Inhibiting Herbicides in a French Lolium multiflorum Population. Genes (Basel). 2021 Nov 21;12(11):1838. doi: 10.3390/genes12111838. PMID: 34828444; PMCID: PMC8620607. 8: Vázquez-García JG, Torra J, Palma-Bautista C, Alcántara-de la Cruz R, Prado R. Point Mutations and Cytochrome P450 Can Contribute to Resistance to ACCase- Inhibiting Herbicides in Three Phalaris Species. Plants (Basel). 2021 Aug 19;10(8):1703. doi: 10.3390/plants10081703. PMID: 34451748; PMCID: PMC8401167. 9: Luo R, Shen B, Xiang P, Liu W. Determination of twenty herbicides in blood by ultrapressure liquid chromatography-tandem mass spectrometry. Forensic Sci Int. 2021 Oct;327:110910. doi: 10.1016/j.forsciint.2021.110910. Epub 2021 Jul 20. PMID: 34425306. 10: Adams E, Gerstle V, Schmitt T, Brühl CA. Co-formulants and adjuvants affect the acute aquatic and terrestrial toxicity of a cycloxydim herbicide formulation to European common frogs (Rana temporaria). Sci Total Environ. 2021 Oct 1;789:147865. doi: 10.1016/j.scitotenv.2021.147865. Epub 2021 May 20. PMID: 34051497. 11: Jursík M, Hamouzová K, Hajšlová J. Dynamics of the Degradation of Acetyl-CoA Carboxylase Herbicides in Vegetables. Foods. 2021 Feb 12;10(2):405. doi: 10.3390/foods10020405. PMID: 33673116; PMCID: PMC7918062. 12: Golmohammadzadeh S, Rojano-Delgado AM, Vázquez-García JG, Romano Y, Osuna MD, Gherekhloo J, De Prado R. Cross-resistance mechanisms to ACCase-inhibiting herbicides in short-spike canarygrass (Phalaris brachystachys). Plant Physiol Biochem. 2020 Jun;151:681-688. doi: 10.1016/j.plaphy.2020.03.037. Epub 2020 Apr 20. PMID: 32353674. 13: Durall C, Lindberg P, Yu J, Lindblad P. Increased ethylene production by overexpressing phosphoenolpyruvate carboxylase in the cyanobacterium Synechocystis PCC 6803. Biotechnol Biofuels. 2020 Jan 28;13:16. doi: 10.1186/s13068-020-1653-y. PMID: 32010220; PMCID: PMC6988332. 14: Rosculete CA, Bonciu E, Rosculete E, Olaru LA. Determination of the Environmental Pollution Potential of Some Herbicides by the Assessment of Cytotoxic and Genotoxic Effects on Allium cepa. Int J Environ Res Public Health. 2018 Dec 28;16(1):75. doi: 10.3390/ijerph16010075. PMID: 30597898; PMCID: PMC6339023. 15: European Food Safety Authority (EFSA); Brancato A, Brocca D, Carrasco Cabrera L, De Lentdecker C, Erdos Z, Ferreira L, Greco L, Jarrah S, Kardassi D, Leuschner R, Lostia A, Lythgo C, Medina P, Miron I, Molnar T, Pedersen R, Reich H, Riemenschneider C, Sacchi A, Santos M, Stanek A, Sturma J, Tarazona J, Theobald A, Vagenende B, Villamar-Bouza L. Modification of the existing maximum residue level for cycloxydim in strawberries. EFSA J. 2018 Aug 31;16(8):e05404. doi: 10.2903/j.efsa.2018.5404. PMID: 32626036; PMCID: PMC7009750. 16: Yuan Q, Toroz D, Kidley N, Gould IR. Mechanism of Photoinduced Triplet Intermolecular Hydrogen Transfer between Cycloxydim and Chlorothalonil. J Phys Chem A. 2018 May 3;122(17):4285-4293. doi: 10.1021/acs.jpca.7b12523. Epub 2018 Apr 20. PMID: 29659278. 17: Belz RG, Farooq MB, Wagner J. Does selective hormesis impact herbicide resistance evolution in weeds? ACCase-resistant populations of Alopecurus myosuroides Huds. as a case study. Pest Manag Sci. 2018 Aug;74(8):1880-1891. doi: 10.1002/ps.4890. Epub 2018 Mar 22. PMID: 29446872. 18: Wagner N, Veith M, Lötters S, Viertel B. Population and life-stage-specific effects of two herbicide formulations on the aquatic development of European common frogs (Rana temporaria). Environ Toxicol Chem. 2017 Jan;36(1):190-200. doi: 10.1002/etc.3525. Epub 2016 Jul 29. Erratum in: Environ Toxicol Chem. 2017 Jan;36(1):276. doi: 10.1002/etc.3573. PMID: 27291460. 19: Wagner N, Lötters S, Veith M, Viertel B. Acute Toxic Effects of the Herbicide Formulation Focus(®) Ultra on Embryos and Larvae of the Moroccan Painted Frog, Discoglossus scovazzi. Arch Environ Contam Toxicol. 2015 Nov;69(4):535-44. doi: 10.1007/s00244-015-0176-1. Epub 2015 Jun 29. PMID: 26118991. 20: Wagner N, Lötters S, Veith M, Viertel B. Effects of an environmentally relevant temporal application scheme of low herbicide concentrations on larvae of two anuran species. Chemosphere. 2015 Sep;135:175-81. doi: 10.1016/j.chemosphere.2015.04.028. Epub 2015 May 15. PMID: 25950411.