OUN87710 | CAS#502887-71-0 | MMP-9 inhibitor

MedKoo Cat#: 555790 | Name: OUN87710

Description:

WARNING: This product is for research use only, not for human or veterinary use.

OUN87710, also known as MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor. OUN87710 can potentially significantly improve the amount of citric acid synthase in bone marrow mesenchymal stem cells to promote cellular citric acid synthesis, and further enhance bone remodeling. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

OUN87710

CAS#502887-71-0

Theoretical Analysis

MedKoo Cat#: 555790

Name: OUN87710

CAS#: 502887-71-0

Chemical Formula: C16H17F2N3O3S

Exact Mass: 369.0959

Molecular Weight: 369.39

Elemental Analysis: C, 52.03; H, 4.64; F, 10.29; N, 11.38; O, 12.99; S, 8.68

Price and Availability

Size	Price	Availability
100mg	USD 950.00	2 Weeks
200mg	USD 1,650.00	2 Weeks
500mg	USD 2,950.00	2 Weeks
1g	USD 4,250.00	2 Weeks

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Related CAS #

No Data

Synonym

MMP-9-IN-1; MMP-9-IN1; MMP9-IN-1; OUN87710; OUN-87710; OUN 87710;

IUPAC/Chemical Name

N-(4-(difluoromethoxy)phenyl)-2-((6-oxo-4-propyl-1,6-dihydropyrimidin-2-yl)thio)acetamide

InChi Key

OLTRRVUORWPRGF-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H17F2N3O3S/c1-2-3-11-8-13(22)21-16(20-11)25-9-14(23)19-10-4-6-12(7-5-10)24-15(17)18/h4-8,15H,2-3,9H2,1H3,(H,19,23)(H,20,21,22)

SMILES Code

O=C(NC1=CC=C(OC(F)F)C=C1)CSC2=NC(CCC)=CC(N2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	Soluble in DMSO	0.0	0.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 369.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

[1]. Dufour A, et al. Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9. Cancer Res. 2011 Jul 15;71(14):4977-88. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138841/) [2]. Da W, Jiang W, Tao L. ROS/MMP-9 mediated CS degradation in BMSC inhibits citric acid metabolism participating in the dual regulation of bone remodelling. Cell Death Discov. 2024 Feb 14;10(1):77. doi: 10.1038/s41420-024-01835-5. PMID: 38355572; PMCID: PMC10866869.