MedKoo Cat#: 597229 | Name: Folitixorin calcium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Folitixorin calcium is an antineoplastic enhancing drug.

Chemical Structure

Folitixorin calcium
Folitixorin calcium
CAS#133978-75-3 (calcium)

Theoretical Analysis

MedKoo Cat#: 597229

Name: Folitixorin calcium

CAS#: 133978-75-3 (calcium)

Chemical Formula: C20H22CaN7O6

Exact Mass: 0.0000

Molecular Weight: 496.51

Elemental Analysis: C, 48.38; H, 4.47; Ca, 8.07; N, 19.75; O, 19.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Folitixorin calcium; CoFactor; ANX-510; ANX 510; ANX510;
IUPAC/Chemical Name
calcium;(2S)-2-[[4-(3-amino-1-oxo-2,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioate
InChi Key
AKUPTUNGFOADRT-ZEDZUCNESA-L
InChi Code
InChI=1S/C20H23N7O6.Ca/c21-20-24-16-15(18(31)25-20)27-9-26(8-12(27)7-22-16)11-3-1-10(2-4-11)17(30)23-13(19(32)33)5-6-14(28)29;/h1-4,12-13H,5-9H2,(H,23,30)(H,28,29)(H,32,33)(H4,21,22,24,25,31);/q;+2/p-2/t12?,13-;/m0./s1
SMILES Code
O=C([O-])[C@@H](NC(C1=CC=C(N2CN3C4=C(N=C(N)NC4=O)NCC3C2)C=C1)=O)CCC([O-])=O.[Ca+2]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 496.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Luu VZ, Chowdhury B, Al-Omran M, Hess DA, Verma S. Role of endothelial primary cilia as fluid mechanosensors on vascular health. Atherosclerosis. 2018 Jun 15;275:196-204. doi: 10.1016/j.atherosclerosis.2018.06.818. [Epub ahead of print] Review. PubMed PMID: 29945035. 2: Chetsawang J, Nudmamud-Thanoi S, Phonchai R, Abubakar Z, Govitrapong P, Chetsawang B. Methamphetamine toxicity-induced calcineurin activation, nuclear translocation of nuclear factor of activated T-cells and elevation of cyclooxygenase 2 levels are averted by calpastatin overexpression in neuroblastoma SH-SY5Y cells. Neurotoxicology. 2018 Jun 23. pii: S0161-813X(18)30233-X. doi: 10.1016/j.neuro.2018.06.011. [Epub ahead of print] PubMed PMID: 29944913. 3: Capetian P, Stanslowsky N, Bernhardi E, Grütz K, Domingo A, Brüggemann N, Naujock M, Seibler P, Klein C, Wegner F. Altered glutamate response and calcium dynamics in iPSC-derived striatal neurons from XDP patients. Exp Neurol. 2018 Jun 23. pii: S0014-4886(18)30202-4. doi: 10.1016/j.expneurol.2018.06.012. [Epub ahead of print] PubMed PMID: 29944858. 4: Bani Hassan E, Nouri M, Vogrin S, Pyman M. Can neutral dietary cation-anion difference (DCAD) decrease occurrence of clinical periparturient hypocalcaemia in dairy cattle? Aust Vet J. 2018 Jul;96(7):269-273. doi: 10.1111/avj.12712. PubMed PMID: 29944750. 5: Chrisostomo KR, Skare TL, Kulak J Jr, Urbanetz AA, Chrisostomo ER, Nisihara R. The prevalence and clinical associations of hypovitaminosis D in pregnant women from Brazil. Int J Gynaecol Obstet. 2018 Jun 26. doi: 10.1002/ijgo.12575. [Epub ahead of print] PubMed PMID: 29944737. 6: Villegas AM, Berghaus R, Zavala G, Barrios MA, França M. Profiling of Egg Layer Flocks Affected with Focal Duodenal Necrosis Based on a Questionnaire Survey. Avian Dis. 2018 Jun;62(2):241-246. doi: 10.1637/11783-121617-ResNote.1. PubMed PMID: 29944407. 7: Alam MS, Takahashi S, Ito M, Suzuki M, Komura M, Sangsriratanakul N, Shoham D, Takehara K. Bactericidal Efficacy of Food Additive-Grade Calcium Hydroxide Against Salmonella Infantis on Eggshells. Avian Dis. 2018 Jun;62(2):177-183. doi: 10.1637/11677-052117-Reg.1. PubMed PMID: 29944400. 8: Cui X, Murakami T, Tamura Y, Aoki K, Hoshino Y, Miura Y. Bacterial inhibition and osteoblasts adhesion on Ti alloy surfaces modified by poly(PEGMA-r-Phosmer) coating. ACS Appl Mater Interfaces. 2018 Jun 26. doi: 10.1021/acsami.8b07757. [Epub ahead of print] PubMed PMID: 29944334. 9: Jacob AD, Ramsaran AI, Mocle AJ, Tran LM, Yan C, Frankland PW, Josselyn SA. A Compact Head-Mounted Endoscope for In Vivo Calcium Imaging in Freely Behaving Mice. Curr Protoc Neurosci. 2018 Jun 26:e51. doi: 10.1002/cpns.51. [Epub ahead of print] PubMed PMID: 29944206. 10: Cheetham CEJ. Multiphoton Intravital Calcium Imaging. Curr Protoc Cytom. 2018 Jun 26:e40. doi: 10.1002/cpcy.40. [Epub ahead of print] PubMed PMID: 29944202. 11: Sheikhi A, Afewerki S, Oklu R, Gaharwar AK, Khademhosseini A. Effect of ionic strength on shear-thinning nanoclay-polymer composite hydrogels. Biomater Sci. 2018 Jun 26. doi: 10.1039/c8bm00469b. [Epub ahead of print] PubMed PMID: 29944151. 12: Zhong X, Chen B, Yang Z. Nanocochleates as the Potential Delivery Systems for Oral Antitumor of Hydroxycamptothecin. J Biomed Nanotechnol. 2018 Jul 1;14(7):1339-1346. doi: 10.1166/jbn.2018.2572. PubMed PMID: 29944107. 13: Dan M, Wen H, Shao A, Xu L. Silver Nanoparticle Exposure Induces Neurotoxicity in the Rat Hippocampus Without Increasing the Blood-Brain Barrier Permeability. J Biomed Nanotechnol. 2018 Jul 1;14(7):1330-1338. doi: 10.1166/jbn.2018.2563. PubMed PMID: 29944106. 14: Silva Andrade A, Marcon Szymanski M, Hashizume LN, Santos Mundstock K, Ferraz Goularte J, Hauber Gameiro G. Evaluation of stress biomarkers and electrolytes in saliva of patients undergoing fixed orthodontic treatment. Minerva Stomatol. 2018 Aug;67(4):172-178. doi: 10.23736/S0026-4970.18.04025-6. PubMed PMID: 29943947. 15: Huang KF, Ma KH, Hung YC, Lo LC, Lin KC, Liu PS, Hu MK, Chueh SH. A new copper ionophore DPMQ protects cells against ultraviolet B irradiation by inhibiting the TRPV1 channel. J Cell Physiol. 2018 Jun 26. doi: 10.1002/jcp.26861. [Epub ahead of print] PubMed PMID: 29943824. 16: Sun Y, Wang P, Li H, Dai J. BMAL1 and CLOCK proteins in regulating UVB-induced apoptosis and DNA damage responses in human keratinocytes. J Cell Physiol. 2018 Jun 26. doi: 10.1002/jcp.26859. [Epub ahead of print] PubMed PMID: 29943823. 17: Castro-Eguiluz D, Leyva-Islas JA, Luvian-Morales J, Martínez-Roque V, Sánchez-López M, Trejo-Durán G, Jiménez-Lima R, Leyva-Rendón FJ. Nutrient Recommendations for Cancer Patients Treated with Pelvic Radiotherapy, with or without Comorbidities. Rev Invest Clin. 2018;70(3):130-135. doi: 10.24875/RIC.18002526. PubMed PMID: 29943773. 18: Muhsen IN, AlFreihi O, Abaalkhail F, AlKhenizan A, Khan M, Eldali A, Alsohaibani F. Bone mineral density loss in patients with cirrhosis. Saudi J Gastroenterol. 2018 Jun 20. doi: 10.4103/sjg.SJG_74_18. [Epub ahead of print] PubMed PMID: 29943736. 19: Han K, Pang F, Cao J, Huo N, Zhang H, Chang H. [Fermentation of sheep bone enzymatic hydrolysates by Lactobacillus plantarum]. Sheng Wu Gong Cheng Xue Bao. 2018 Jun 25;34(6):945-955. doi: 10.13345/j.cjb.170453. Chinese. PubMed PMID: 29943540. 20: Sen KS, Duarte Campos DF, Köpf M, Blaeser A, Fischer H. The Effect of Addition of Calcium Phosphate Particles to Hydrogel-Based Composite Materials on Stiffness and Differentiation of Mesenchymal Stromal Cells toward Osteogenesis. Adv Healthc Mater. 2018 Jun 25:e1800343. doi: 10.1002/adhm.201800343. [Epub ahead of print] PubMed PMID: 29943520.