Geodiamolide A | CAS#108675-63-4 | cyclodepsipeptide

MedKoo Cat#: 596812 | Name: Geodiamolide A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Geodiamolide A is a cyclodepsipeptide.

Chemical Structure

Geodiamolide A

CAS#108675-63-4

Theoretical Analysis

MedKoo Cat#: 596812

Name: Geodiamolide A

CAS#: 108675-63-4

Chemical Formula: C28H40IN3O6

Exact Mass: 641.1962

Molecular Weight: 641.54

Elemental Analysis: C, 52.42; H, 6.28; I, 19.78; N, 6.55; O, 14.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Geodiamolide A;

IUPAC/Chemical Name

(S)-2-amino-N-((2S,4R,5R,7E,9E,11R,13S)-2-amino-5-formyl-13-hydroxy-4-(4-hydroxy-3-iodophenyl)-7,9,11-trimethyl-3,6-dioxotetradeca-7,9-dien-5-yl)-N-methylpropanamide

InChi Key

AAHYELOHRHVDCH-HWCOUVQTSA-N

InChi Code

InChI=1S/C28H40IN3O6/c1-15(10-16(2)12-18(4)34)11-17(3)26(37)28(14-33,32(7)27(38)20(6)31)24(25(36)19(5)30)21-8-9-23(35)22(29)13-21/h8-11,13-14,16,18-20,24,34-35H,12,30-31H2,1-7H3/b15-10+,17-11+/t16-,18-,19-,20-,24-,28-/m0/s1

SMILES Code

CN(C([C@H](C)N)=O)[C@@]([C@H](C([C@H](C)N)=O)c1ccc(O)c(I)c1)(C(/C(C)=C/C(C)=C/[C@H](C)C[C@@H](O)C)=O)C=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 641.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Rangel M, Ionta M, Cristina Pfister S, Adolpho Sant'anna Ferreira R, Maria Machado-Santelli G. Marine sponge depsipeptide increases gap junction length in HTC cells transfected with Cx43-GFP. Cell Biol Int Rep (2010). 2010;17(1):e00003. doi: 10.1042/CBR20100003. Epub 2010 Aug 11. PubMed PMID: 23119141; PubMed Central PMCID: PMC3476824. 2: Rangel M, Prado MP, Konno K, Naoki H, Freitas JC, Machado-Santelli GM. Cytoskeleton alterations induced by Geodia corticostylifera depsipeptides in breast cancer cells. Peptides. 2006 Sep;27(9):2047-57. Epub 2006 Jul 14. PubMed PMID: 16843570. 3: Stingl J, Andersen RJ, Emerman JT. In vitro screening of crude extracts and pure metabolites obtained from marine invertebrates for the treatment of breast cancer. Cancer Chemother Pharmacol. 1992;30(5):401-6. PubMed PMID: 1505079.