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MedKoo Cat#: 596771 | Name: Bilanafos sodium
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bialaphos is a natural non-selective phytotoxin produced by certain Streptomyces species. It is a pro-toxin, a tripeptide that is converted in vivo to the active agent phosphinothricin, which is a glutamine analog. L-Phosphinothricin inhibits glutamine synthetase (Ki = 6.1 µM), resulting in accumulation of ammonium and disruption of primary metabolism. The bacterial bar gene encodes a phosphinothricin acetyltransferase, which confers resistance to phosphinothricin.3 Bialaphos is used in the selection of transgenic plants that express the bar gene, usually under the control of a constitutively active viral promoter.

Chemical Structure

Bilanafos sodium
Bilanafos sodium
CAS#71048-99-2 (sodium)

Theoretical Analysis

MedKoo Cat#: 596771

Name: Bilanafos sodium

CAS#: 71048-99-2 (sodium)

Chemical Formula: C11H21N3NaO6P

Exact Mass: 0.0000

Molecular Weight: 345.26

Elemental Analysis: C, 38.27; H, 6.13; N, 12.17; Na, 6.66; O, 27.80; P, 8.97

Price and Availability

Size Price Availability Quantity
10mg USD 325.00 2 Weeks
50mg USD 850.00 2 Weeks
100mg USD 1,150.00 2 Weeks
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Related CAS #
35597-43-4 (free acid) 71048-99-2 (sodium)
Synonym
Bilanafos-sodium; MW 801; SF 1293; SF1293; SF-1293; Bialaphos sodium;
IUPAC/Chemical Name
sodium (2-amino-4-((hydroxymethyl)hydrophosphoryl)butanoyl)-L-alanyl-L-alaninate
InChi Key
ABIKTJOYXWTPDS-NKGRROCASA-M
InChi Code
InChI=1S/C11H22N3O6P.Na/c1-6(9(16)14-7(2)11(18)19)13-10(17)8(12)3-4-21(20)5-15;/h6-8,15,21H,3-5,12H2,1-2H3,(H,13,17)(H,14,16)(H,18,19);/q;+1/p-1/t6-,7-,8?;/m0./s1
SMILES Code
C[C@@H](C([O-])=O)NC([C@H](C)NC(C(N)CCP(CO)=O)=O)=O.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 345.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bilanakis N. Psychogenic urinary retention. Gen Hosp Psychiatry. 2006 May- Jun;28(3):259-61. doi: 10.1016/j.genhosppsych.2006.01.002. PMID: 16675372. 2: Bilanakis N, Vratsista A, Siorou S. A brain ependymoma with psychiatric manifestation. J BUON. 2017 Nov-Dec;22(6):1604-1605. PMID: 29332363. 3: Bilanakis N, Peritogiannis VK, Vratsista A. Treatment decision-making capacity in hospitalized patients with schizophrenia. Psychiatriki. 2017 Jan- Mar;28(1):37-45. doi: 10.22365/jpsych.2017.281.37. PMID: 28541237. 4: Bilanakis N, Peritogiannis V. Attitudes of patients and families toward restraint and seclusion. Psychiatr Serv. 2008 Oct;59(10):1220. doi: 10.1176/ps.2008.59.10.1220. PMID: 18832516. 5: Bilanakis N, Peritogiannis V, Kalampokis G. Infections as complications of neuroleptic malignant syndrome. World J Biol Psychiatry. 2009;10(4 Pt 3):973-6. doi: 10.1080/15622970801935578. PMID: 18609425. 6: Hargarter L, Bergmans P, Cherubin P, Keim S, Conca A, Serrano-Blanco A, Bitter I, Bilanakis N, Schreiner A. Once-monthly paliperidone palmitate in recently diagnosed and chronic non-acute patients with schizophrenia. Expert Opin Pharmacother. 2016 Jun;17(8):1043-53. doi: 10.1080/14656566.2016.1174692. Epub 2016 May 9. PMID: 27042990; PMCID: PMC4898156. 7: Bilanakis N, Vratsista A, Athanasiou E, Niakas D, Peritogiannis V. Medical patients' treatment decision making capacity: a report from a general hospital in Greece. Clin Pract Epidemiol Ment Health. 2014 Nov 26;10:133-9. doi: 10.2174/1745017901410010133. PMID: 25505489; PMCID: PMC4260233. 8: Zouvelou V, Yubero D, Apostolakopoulou L, Kokkinou E, Bilanakis M, Dalivigka Z, Nikas I, Kollia E, Perez-Dueñas B, Macaya A, Marcé-Grau A, Voutetakis A, Anagnostopoulou K, Kekou K, Sofocleus C, Veltra D, Kokkinis X, Fryssira H, Torres RJ, Amstrong J, Santorelli FM, Artuch R, Pons R. The genetic etiology in cerebral palsy mimics: The results from a Greek tertiary care center. Eur J Paediatr Neurol. 2019 May;23(3):427-437. doi: 10.1016/j.ejpn.2019.02.001. Epub 2019 Feb 14. PMID: 30799092. 9: Bilanakis N, Papamichael G, Peritogiannis V. Chemical restraint in routine clinical practice: a report from a general hospital psychiatric ward in Greece. Ann Gen Psychiatry. 2011 Feb 24;10:4. doi: 10.1186/1744-859X-10-4. PMID: 21349171; PMCID: PMC3050779. 10: Bilanakis N, Kalampokis G, Christou K, Peritogiannis V. Use of coercive physical measures in a psychiatric ward of a general hospital in Greece. Int J Soc Psychiatry. 2010 Jul;56(4):402-11. doi: 10.1177/0020764009106620. Epub 2009 Jul 23. PMID: 19628555. 11: Bilanakis N, Madianos MG, Liakos A. Psychiatric morbidity among repatriated Greek migrants in a rural area. Eur Arch Psychiatry Clin Neurosci. 1995;245(1):36-44. doi: 10.1007/BF02191542. PMID: 7786910. 12: Bilanakis N, Vratsista A, Kalampokis G, Papamichael G, Peritogiannis V. The Greek version of the MacArthur competence assessment tool for treatment: reliability and validity. Evaluation of capacity for treatment decisions in Greek psychiatric patients. Ann Gen Psychiatry. 2013 Apr 9;12(1):10. doi: 10.1186/1744-859X-12-10. PMID: 23570333; PMCID: PMC3648422. 13: Bilanakis N, Gibiriti M. Lithium intoxication, hypercalcemia and "accidentally" induced food and water aversion: a case report. Prog Neuropsychopharmacol Biol Psychiatry. 2004 Jan;28(1):201-3. doi: 10.1016/S0278-5846(03)00167-2. PMID: 14687875. 14: Bilanakis N. [Compulsory hospitalization: α case of conflict between the psychiatrist and the persecutor due to the obscurity of the law]. Psychiatriki. 2012 Jul-Sep;23(3):255-61. Greek, Modern. PMID: 23073548. 15: Geitona M, Ollandezos M, Kousoulakou C, Agelopoulos E, Zaharakis K, Kakavas P, Karpouza B, Kesidou S, Bilanakis N, Papamichael E, Papanicolaou S, Chaidemenos A, Chamogeorgakis T, Kyriopoulos J. [The cost of treating schizophrenia in Greece]. Psychiatriki. 2007 Jan;18(1):47-58. Greek, Modern. PMID: 22466429.

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