MedKoo Cat#: 591285 | Name: Etoperidone hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Etoperidone hydrochloride is an antidepressant.

Chemical Structure

Etoperidone hydrochloride
Etoperidone hydrochloride
CAS#57775-22-1 (HCl)

Theoretical Analysis

MedKoo Cat#: 591285

Name: Etoperidone hydrochloride

CAS#: 57775-22-1 (HCl)

Chemical Formula: C19H29Cl2N5O

Exact Mass:

Molecular Weight: 414.38

Elemental Analysis: C, 55.07; H, 7.05; Cl, 17.11; N, 16.90; O, 3.86

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Synonym
Etoperidone hydrochloride; NSC 304398; NSC-304398; NSC304398
IUPAC/Chemical Name
2-(3-(4-(3-Chlorophenyl)piperazin-1-yl)propyl)-4,5-diethyl-2,4-dihydro-3H-1,2,4-triazol-3-one monohydrochloride
InChi Key
BHKPQZVLIZKSAG-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H28ClN5O.ClH/c1-3-18-21-25(19(26)24(18)4-2)10-6-9-22-11-13-23(14-12-22)17-8-5-7-16(20)15-17;/h5,7-8,15H,3-4,6,9-14H2,1-2H3;1H
SMILES Code
O=C1N(CCCN2CCN(C3=CC=CC(Cl)=C3)CC2)N=C(CC)N1CC.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 414.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Caldwell GW, Wu WN, Masucci JA. Evaluation of the absorption, excretion and metabolism of [14C] etoperidone in man. Xenobiotica. 2001 Nov;31(11):823-39. PubMed PMID: 11765144. 2: Janiri L, Salera P, Tempesta E. Inhibitory effects of etoperidone on the spontaneous activity of brainstem neurones and their excitatory responses to some putative transmitters. Arzneimittelforschung. 1986 Dec;36(12):1721-6. PubMed PMID: 2882758. 3: Ramacci MT, Ghirardi O, Maccari F, Pacifici L, Sale P. Pharmacological evaluation of delta2, 1,2,4-triazolin-5-one [1,3(4-m-chlorophenyl-1-piperazinyl)-propyl]-3,4-diethyl-hydrochloride (Etoperidone), a new potential antidepressant drug. Arzneimittelforschung. 1979;29(2):294-307. PubMed PMID: 582144.