MedKoo Cat#: 596303 | Name: JTE 7-31

Description:

WARNING: This product is for research use only, not for human or veterinary use.

JTE 7-31 is a selective cannabinoid receptor agonist. It is a reasonably highly selective CB2 agonist, but still retains appreciable affinity at CB1, with a Ki of 0.088nM at CB2 vs 11nM at CB1

Chemical Structure

JTE 7-31
JTE 7-31
CAS#194358-72-0

Theoretical Analysis

MedKoo Cat#: 596303

Name: JTE 7-31

CAS#: 194358-72-0

Chemical Formula: C22H28N2O3

Exact Mass: 368.2100

Molecular Weight: 368.47

Elemental Analysis: C, 71.71; H, 7.66; N, 7.60; O, 13.03

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
JTE 7-31;
IUPAC/Chemical Name
2-(4-hydroxyphenethyl)-5-methoxy-4-(pentylamino)isoindolin-1-one
InChi Key
FMUMUYFMLZGXJR-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H28N2O3/c1-3-4-5-13-23-21-19-15-24(14-12-16-6-8-17(25)9-7-16)22(26)18(19)10-11-20(21)27-2/h6-11,23,25H,3-5,12-15H2,1-2H3
SMILES Code
O=C1N(CCC2=CC=C(O)C=C2)CC3=C1C=CC(OC)=C3NCCCCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 368.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhou EH, Paolucci M, Dryja TP, Manley T, Xiang C, Rice DS, Prasanna G, Chen A. A Compact Whole-Eye Perfusion System to Evaluate Pharmacologic Responses of Outflow Facility. Invest Ophthalmol Vis Sci. 2017 Jun 1;58(7):2991-3003. doi: 10.1167/iovs.16-20974. PubMed PMID: 28605810. 2: Salort G, Álvaro-Bartolomé M, García-Sevilla JA. Regulation of cannabinoid CB(2) receptor constitutive activity in vivo: repeated treatments with inverse agonists reverse the acute activation of JNK and associated apoptotic signaling in mouse brain. Psychopharmacology (Berl). 2017 Mar;234(6):925-941. doi: 10.1007/s00213-017-4537-5. Epub 2017 Jan 26. PubMed PMID: 28127623.