Jam 2-263 | CAS#134782-23-3 | catechol siderophore-carbacephalosporin

MedKoo Cat#: 596104 | Name: JAM2-263

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Jam 2-263 is a spermidine-based catechol siderophore-carbacephalosporin.

Chemical Structure

JAM2-263

CAS#134782-23-3

Theoretical Analysis

MedKoo Cat#: 596104

Name: JAM2-263

CAS#: 134782-23-3

Chemical Formula: C33H38ClN5O11

Exact Mass: 715.2256

Molecular Weight: 716.14

Elemental Analysis: C, 55.35; H, 5.35; Cl, 4.95; N, 9.78; O, 24.57

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Jam 2-263; Jam-2-263; Jam2263; Jam 2 263l;

IUPAC/Chemical Name

(6R,7S)-3-chloro-7-(4-((4-(2,3-dihydroxybenzamido)butyl)(3-(2,3-dihydroxybenzamido)propyl)amino)-4-oxobutanamido)-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

InChi Key

JPWNHFIUVFVMIF-RLWLMLJZSA-N

InChi Code

InChI=1S/C33H38ClN5O11/c34-20-10-11-21-26(32(48)39(21)27(20)33(49)50)37-24(42)12-13-25(43)38(17-5-15-36-31(47)19-7-4-9-23(41)29(19)45)16-2-1-14-35-30(46)18-6-3-8-22(40)28(18)44/h3-4,6-9,21,26,40-41,44-45H,1-2,5,10-17H2,(H,35,46)(H,36,47)(H,37,42)(H,49,50)/t21-,26+/m1/s1

SMILES Code

O=C(C(N12)=C(Cl)CC[C@]2([H])[C@H](NC(CCC(N(CCCCNC(C3=CC=CC(O)=C3O)=O)CCCNC(C4=CC=CC(O)=C4O)=O)=O)=O)C1=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 716.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Brochu A, Brochu N, Nicas TI, Parr TR Jr, Minnick AA Jr, Dolence EK, McKee JA, Miller MJ, Lavoie MC, Malouin F. Modes of action and inhibitory activities of new siderophore-beta-lactam conjugates that use specific iron uptake pathways for entry into bacteria. Antimicrob Agents Chemother. 1992 Oct;36(10):2166-75. PubMed PMID: 1444296; PubMed Central PMCID: PMC245471.