L 702007 | CAS#139547-89-0 | HIV-1 reverse transcriptase inhibitor

MedKoo Cat#: 596673 | Name: L 702007

Description:

WARNING: This product is for research use only, not for human or veterinary use.

L 702007 is a HIV-1 reverse transcriptase inhibitor.

Chemical Structure

L 702007

CAS#139547-89-0

Theoretical Analysis

MedKoo Cat#: 596673

Name: L 702007

CAS#: 139547-89-0

Chemical Formula: C18H25N3O2

Exact Mass: 315.1947

Molecular Weight: 315.41

Elemental Analysis: C, 68.54; H, 7.99; N, 13.32; O, 10.14

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

L 702007; L-702007; L702007; 5-Emmpo;

IUPAC/Chemical Name

5-ethyl-3-(((5-ethyl-2-methoxy-6-methylpyridin-3-yl)methyl)amino)-6-methylpyridin-2(1H)-one

InChi Key

IUKVADMYSQZSIH-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H25N3O2/c1-6-13-8-15(18(23-5)21-12(13)4)10-19-16-9-14(7-2)11(3)20-17(16)22/h8-9,19H,6-7,10H2,1-5H3,(H,20,22)

SMILES Code

O=C1C(NCC2=CC(CC)=C(C)N=C2OC)=CC(CC)=C(C)N1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 315.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Woolf EJ, Matuszewski B. Simultaneous determination of L-702,007, a HIV-1 reverse transcriptase inhibitor, and its 6-hydroxy metabolite in human plasma by column-switching high-performance liquid chromatography with fluorescence detection. J Chromatogr A. 1996 Apr 5;729(1-2):211-7. PubMed PMID: 9004942. 2: Wai JS, Williams TM, Bamberger DL, Fisher TE, Hoffman JM, Hudcosky RJ, MacTough SC, Rooney CS, Saari WS, Thomas CM, et al. Synthesis and evaluation of 2-pyridinone derivatives as specific HIV-1 reverse transcriptase inhibitors. 3. Pyridyl and phenyl analogs of 3-aminopyridin-2(1H)-one. J Med Chem. 1993 Jan 22;36(2):249-55. PubMed PMID: 7678654.