MedKoo Cat#: 571594 | Name: Pyrophosphoric acid, chloromethyl trimethyl ester

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pyrophosphoric acid, chloromethyl trimethyl ester is an agricultural biochemical.

Chemical Structure

Pyrophosphoric acid, chloromethyl trimethyl ester
Pyrophosphoric acid, chloromethyl trimethyl ester
CAS#3309-75-9

Theoretical Analysis

MedKoo Cat#: 571594

Name: Pyrophosphoric acid, chloromethyl trimethyl ester

CAS#: 3309-75-9

Chemical Formula: C4H11ClO7P2

Exact Mass: 267.9669

Molecular Weight: 268.52

Elemental Analysis: C, 17.89; H, 4.13; Cl, 13.20; O, 41.71; P, 23.07

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
ACR 58-26; ACR58-26; ACR-58-26
IUPAC/Chemical Name
Pyrophosphoric acid, chloromethyl trimethyl ester
InChi Key
IEMSLTORIGZKGC-UHFFFAOYSA-N
InChi Code
InChI=1S/C4H11ClO7P2/c1-8-13(6,9-2)12-14(7,10-3)11-4-5/h4H2,1-3H3
SMILES Code
O=P(OC)(OP(OC)(OC)=O)OCCl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 268.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ji B, Zhao C, Yan K, Sun G. Effects of divalent anionic catalysts on cross-linking of cellulose with 1,2,3,4-butanetetracarboxylic acid. Carbohydr Polym. 2018 Feb 1;181:292-299. doi: 10.1016/j.carbpol.2017.10.081. Epub 2017 Oct 23. PubMed PMID: 29253975. 2: Shornikov A, Tran H, Macias J, Halavaty AS, Minasov G, Anderson WF, Kuhn ML. Structure of the Bacillus anthracis dTDP-L-rhamnose-biosynthetic enzyme dTDP-4-dehydrorhamnose 3,5-epimerase (RfbC). Acta Crystallogr F Struct Biol Commun. 2017 Dec 1;73(Pt 12):664-671. doi: 10.1107/S2053230X17015849. Epub 2017 Nov 10. PubMed PMID: 29199987; PubMed Central PMCID: PMC5713671. 3: Atis M, Johnson KA, Elber R. Pyrophosphate Release in the Protein HIV Reverse Transcriptase. J Phys Chem B. 2017 Oct 19;121(41):9557-9565. doi: 10.1021/acs.jpcb.7b08320. Epub 2017 Oct 4. PubMed PMID: 28926712; PubMed Central PMCID: PMC5648621. 4: Puljula E, Turhanen PA. Semi-preparative high-performance countercurrent chromatography method for the purification of chemically synthesized ATP analogue, ApppI. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:180-182. doi: 10.1016/j.jchromb.2017.08.038. Epub 2017 Aug 30. PubMed PMID: 28869872. 5: Cordeiro CD, Saiardi A, Docampo R. The inositol pyrophosphate synthesis pathway in Trypanosoma brucei is linked to polyphosphate synthesis in acidocalcisomes. Mol Microbiol. 2017 Oct;106(2):319-333. doi: 10.1111/mmi.13766. Epub 2017 Aug 22. PubMed PMID: 28792096; PubMed Central PMCID: PMC5630508. 6: Caballero D, Li Y, Fetene J, Ponsetto J, Chen A, Zhu C, Braddock DT, Bergwitz C. Intraperitoneal pyrophosphate treatment reduces renal calcifications in Npt2a null mice. PLoS One. 2017 Jul 13;12(7):e0180098. doi: 10.1371/journal.pone.0180098. eCollection 2017. PubMed PMID: 28704395; PubMed Central PMCID: PMC5509111. 7: Curci A, Gandin V, Marzano C, Hoeschele JD, Natile G, Margiotta N. Novel Kiteplatin Pyrophosphate Derivatives with Improved Efficacy. Inorg Chem. 2017 Jul 3;56(13):7482-7493. doi: 10.1021/acs.inorgchem.7b00931. Epub 2017 Jun 21. PubMed PMID: 28636387. 8: Fischbacher A, von Sonntag C, Schmidt TC. Hydroxyl radical yields in the Fenton process under various pH, ligand concentrations and hydrogen peroxide/Fe(II) ratios. Chemosphere. 2017 Sep;182:738-744. doi: 10.1016/j.chemosphere.2017.05.039. Epub 2017 May 7. PubMed PMID: 28531840. 9: Germain DP. Pseudoxanthoma elasticum. Orphanet J Rare Dis. 2017 May 10;12(1):85. doi: 10.1186/s13023-017-0639-8. Review. PubMed PMID: 28486967; PubMed Central PMCID: PMC5424392. 10: Trofimova ES, Zykova MV, Ligacheva AA, Sherstoboev EY, Zhdanov VV, Belousov MV, Yusubov MS, Krivoshchekov SV, Danilets MG, Dygai AM. Influence of Humic Acids Extracted from Peat by Different Methods on Functional Activity of Macrophages in Vitro. Bull Exp Biol Med. 2017 Apr;162(6):741-745. doi: 10.1007/s10517-017-3702-5. Epub 2017 Apr 20. PubMed PMID: 28429211. 11: Pomozi V, Brampton C, van de Wetering K, Zoll J, Calio B, Pham K, Owens JB, Marh J, Moisyadi S, Váradi A, Martin L, Bauer C, Erdmann J, Aherrahrou Z, Le Saux O. Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice. Am J Pathol. 2017 Jun;187(6):1258-1272. doi: 10.1016/j.ajpath.2017.02.009. Epub 2017 Apr 14. PubMed PMID: 28416300; PubMed Central PMCID: PMC5455066. 12: Anastasiou AD, Strafford S, Posada-Estefan O, Thomson CL, Hussain SA, Edwards TJ, Malinowski M, Hondow N, Metzger NK, Brown CTA, Routledge MN, Brown AP, Duggal MS, Jha A. β-pyrophosphate: A potential biomaterial for dental applications. Mater Sci Eng C Mater Biol Appl. 2017 Jun 1;75:885-894. doi: 10.1016/j.msec.2017.02.116. Epub 2017 Feb 24. PubMed PMID: 28415544. 13: Wang F, Zhang C, Xue Q, Li H, Xian Y. Label-free upconversion nanoparticles-based fluorescent probes for sequential sensing of Cu(2+), pyrophosphate and alkaline phosphatase activity. Biosens Bioelectron. 2017 Sep 15;95:21-26. doi: 10.1016/j.bios.2017.04.010. Epub 2017 Apr 12. PubMed PMID: 28411533. 14: Villa-Bellosta R, Hamczyk MR, Andrés V. Novel phosphate-activated macrophages prevent ectopic calcification by increasing extracellular ATP and pyrophosphate. PLoS One. 2017 Mar 31;12(3):e0174998. doi: 10.1371/journal.pone.0174998. eCollection 2017. PubMed PMID: 28362852; PubMed Central PMCID: PMC5376322. 15: Uitto J, Li Q, van de Wetering K, Váradi A, Terry SF. Insights into Pathomechanisms and Treatment Development in Heritable Ectopic Mineralization Disorders: Summary of the PXE International Biennial Research Symposium-2016. J Invest Dermatol. 2017 Apr;137(4):790-795. doi: 10.1016/j.jid.2016.12.014. Review. PubMed PMID: 28340679; PubMed Central PMCID: PMC5831331. 16: Halling Linder C, Ek-Rylander B, Krumpel M, Norgård M, Narisawa S, Millán JL, Andersson G, Magnusson P. Bone Alkaline Phosphatase and Tartrate-Resistant Acid Phosphatase: Potential Co-regulators of Bone Mineralization. Calcif Tissue Int. 2017 Jul;101(1):92-101. doi: 10.1007/s00223-017-0259-2. Epub 2017 Mar 16. PubMed PMID: 28303318; PubMed Central PMCID: PMC5486932. 17: Daryl Ariawan A, Webb JE, Howe EN, Gale PA, Thordarson P, Hunter L. Cyclic peptide unguisin A is an anion receptor with high affinity for phosphate and pyrophosphate. Org Biomol Chem. 2017 Apr 5;15(14):2962-2967. doi: 10.1039/c7ob00316a. PubMed PMID: 28294280. 18: Wakai S, Abe A, Fujii S, Nakasone K, Sambongi Y. Pyrophosphate hydrolysis in the extremely halophilic archaeon Haloarcula japonica is catalyzed by a single enzyme with a broad ionic strength range. Extremophiles. 2017 May;21(3):471-477. doi: 10.1007/s00792-017-0917-3. Epub 2017 Feb 17. PubMed PMID: 28213825. 19: Wu S. Molecular dynamics simulation study of the "stay or leave" problem for two magnesium ions in gene transcription. Proteins. 2017 Jun;85(6):1002-1007. doi: 10.1002/prot.25268. Epub 2017 Mar 7. PubMed PMID: 28205291. 20: Li Q, Kingman J, van de Wetering K, Tannouri S, Sundberg JP, Uitto J. Abcc6 Knockout Rat Model Highlights the Role of Liver in PPi Homeostasis in Pseudoxanthoma Elasticum. J Invest Dermatol. 2017 May;137(5):1025-1032. doi: 10.1016/j.jid.2016.11.042. Epub 2017 Jan 19. PubMed PMID: 28111129.