MedKoo Cat#: 341216 | Name: Venenatine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Venenatine is a biochemical.

Chemical Structure

Venenatine
Venenatine
CAS#1055-75-0

Theoretical Analysis

MedKoo Cat#: 341216

Name: Venenatine

CAS#: 1055-75-0

Chemical Formula: C22H28N2O4

Exact Mass: 384.2049

Molecular Weight: 384.48

Elemental Analysis: C, 68.73; H, 7.34; N, 7.29; O, 16.64

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Venenatine; NSC 339139; NSC-339139;NSC339139.
IUPAC/Chemical Name
Yohimban-16-carboxylic acid, 17-hydroxy-9-methoxy-, methyl ester, (3-beta,16-beta,17-beta,20-alpha)-
InChi Key
WMMZYEBFJWWUJX-YCSGKXEJSA-N
InChi Code
InChI=1S/C22H28N2O4/c1-27-18-5-3-4-15-19(18)13-8-9-24-11-12-6-7-17(25)20(22(26)28-2)14(12)10-16(24)21(13)23-15/h3-5,12,14,16-17,20,23,25H,6-11H2,1-2H3/t12-,14+,16-,17-,20+/m1/s1
SMILES Code
COC1=CC=CC(N2)=C1C(CCN3C4)=C2[C@@]3([H])C[C@@]5([H])[C@]4([H])CC[C@](O)([H])[C@@]5([H])C(OC)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 384.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ning DS, Peng LY, Lv SH, Li DP, Pan ZH. A new daphnane diterpenoid from Excoecaria venenata with inhibitory effect on human leukaemia HL-60 cells. Nat Prod Res. 2015;29(6):524-8. doi: 10.1080/14786419.2014.953498. Epub 2014 Sep 3. PubMed PMID: 25181934. 2: Lebold TP, Wood JL, Deitch J, Lodewyk MW, Tantillo DJ, Sarpong R. A divergent approach to the synthesis of the yohimbinoid alkaloids venenatine and alstovenine. Nat Chem. 2013 Feb;5(2):126-31. doi: 10.1038/nchem.1528. Epub 2012 Dec 23. PubMed PMID: 23344433; PubMed Central PMCID: PMC3556932. 3: Singh UP, Sarma BK, Mishra PK, Ray AB. Antifungal activity of venenatine, an indole alkaloid isolated from Alstonia venenata. Folia Microbiol (Praha). 2000;45(2):173-6. PubMed PMID: 11271828.