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MedKoo Cat#: 564412 | Name: (R)-N-Desmethyl PK11195

Description:

WARNING: This product is for research use only, not for human or veterinary use.

(R)-N-Desmethyl PK11195 is a precursor for (R)-[N-Methyl-11C-]PK11195.

Chemical Structure

(R)-N-Desmethyl PK11195
(R)-N-Desmethyl PK11195
CAS#157809-85-3

Theoretical Analysis

MedKoo Cat#: 564412

Name: (R)-N-Desmethyl PK11195

CAS#: 157809-85-3

Chemical Formula: C20H19ClN2O

Exact Mass: 338.1186

Molecular Weight: 338.84

Elemental Analysis: C, 70.90; H, 5.65; Cl, 10.46; N, 8.27; O, 4.72

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
(R)-N Desmethyl PK11195; (R) N-Desmethyl PK11195; (R)-N-Desmethyl PK-11195; (R)-N-Desmethyl PK 11195; (R)-N-Desmethyl PK11195
IUPAC/Chemical Name
N-[(2R)-Butan-2-yl]-1-(2-chlorophenyl)isoquinoline-3-carboxamide
InChi Key
XXSIYNJKCPZOFQ-CYBMUJFWSA-N
InChi Code
InChI=1S/C20H19ClN2O/c1-3-13(2)22-20(24)18-12-14-8-4-5-9-15(14)19(23-18)16-10-6-7-11-17(16)21/h4-13H,3H2,1-2H3,(H,22,24)/t13-/m1/s1
SMILES Code
O=C(C1=CC2=C(C(C3=CC=CC=C3Cl)=N1)C=CC=C2)N[C@@H](CC)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 338.84 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Shah F, Hume SP, Pike VW, Ashworth S, McDermott J. Synthesis of the enantiomers of [N-methyl-11C]PK 11195 and comparison of their behaviours as radioligands for PK binding sites in rats. Nucl Med Biol. 1994 May;21(4):573-81. PubMed PMID: 9234314.