2-Phenylacetamide is a metabolite of L-phenylalanine and increases the proliferation of MCF-7 cells, an effect that can be blocked by the estrogen receptor (ER) antagonist ICI 182780. It also increases the levels of luteinizing hormone and estrogen and the expression of estrogen receptor α (ERα) and ERβ in the uterus of immature female mice.
MedKoo Cat#: 112049
Name: 2-Phenylacetamide
CAS#: 103-81-1
Chemical Formula: C8H9NO
Exact Mass: 135.0684
Molecular Weight: 135.17
Elemental Analysis: C, 71.09; H, 6.71; N, 10.36; O, 11.84
Solvent | mg/mL | mM | |
---|---|---|---|
Solubility | |||
DMF | 2.0 | 14.80 | |
DMSO | 2.0 | 14.80 | |
Ethanol | 10.0 | 73.98 |
The following data is based on the product molecular weight 135.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |