MedKoo Cat#: 562175 | Name: DDP-38003 2HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DDP-38003 2HCl is an orally available inhibitor of histone lysine-specific demethylase 1A (LSD1).

Chemical Structure

DDP-38003 2HCl
DDP-38003 2HCl
CAS#1831167-98-6 (HCl)

Theoretical Analysis

MedKoo Cat#: 562175

Name: DDP-38003 2HCl

CAS#: 1831167-98-6 (HCl)

Chemical Formula: C21H28Cl2N4O

Exact Mass: 0.0000

Molecular Weight: 423.38

Elemental Analysis: C, 59.58; H, 6.67; Cl, 16.75; N, 13.23; O, 3.78

Price and Availability

Size Price Availability Quantity
100mg USD 1,450.00 2 Weeks
200mg USD 2,750.00 2 Weeks
500mg USD 3,250.00 2 Weeks
1g USD 4,250.00 2 Weeks
2g USD 6,950.00 2 Weeks
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Related CAS #
Synonym
DDP-38003 2HCl; DDP 38003 2HCl; DDP38003 2HCl; DDP-38003 dihydrochloride; DDP 38003 dihydrochloride; DDP38003 dihydrochloride;
IUPAC/Chemical Name
N-[4-[(1S,2R)-2-Aminocyclopropyl]phenyl]-4-(4-methyl-1-piperazinyl)-benzamide dihydrochloride
InChi Key
HFSFENIQYFFMGC-HUQPAIQZSA-N
InChi Code
InChI=1S/C21H26N4O.2ClH/c1-24-10-12-25(13-11-24)18-8-4-16(5-9-18)21(26)23-17-6-2-15(3-7-17)19-14-20(19)22;;/h2-9,19-20H,10-14,22H2,1H3,(H,23,26);2*1H/t19-,20+;;/m0../s1
SMILES Code
O=C(NC1=CC=C([C@H]2[C@H](N)C2)C=C1)C3=CC=C(N4CCN(C)CC4)C=C3.[H]Cl.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 423.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Nicosia L, Boffo FL, Ceccacci E, Conforti F, Pallavicini I, Bedin F, Ravasio R, Massignani E, Somervaille TCP, Minucci S, Bonaldi T. Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1 oncogenic functions in AML. Oncogene. 2022 Feb;41(6):878-894. doi: 10.1038/s41388-021-02123-7. Epub 2021 Dec 3. PMID: 34862459; PMCID: PMC8830420.