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MedKoo Cat#: 562135 | Name: RUC-4

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RUC-4 is an aIIbß3 antagonist for prehospital therapy of myocardial infarction.

Chemical Structure

RUC-4
RUC-4
CAS#1448313-27-6

Theoretical Analysis

MedKoo Cat#: 562135

Name: RUC-4

CAS#: 1448313-27-6

Chemical Formula: C16H18N8O2S

Exact Mass: 386.1273

Molecular Weight: 386.43

Elemental Analysis: C, 49.73; H, 4.70; N, 29.00; O, 8.28; S, 8.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
1448313-27-6
Synonym
RUC-4; RUC 4; RUC4; ZALUNFIBAN; zalunfiban
IUPAC/Chemical Name
2-Amino-N-[5-[5-oxo-7-(1-piperazinyl)-5H-1,3,4-thiadiazolo[3,2-a]pyrimidin-2-yl]-3-pyridinyl]acetamide
InChi Key
YTFMOSCBEAMELI-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H18N8O2S/c17-9-13(25)20-11-7-10(1-2-19-11)15-22-24-14(26)8-12(21-16(24)27-15)23-5-3-18-4-6-23/h1-2,7-8,18H,3-6,9,17H2,(H,19,20,25)
SMILES Code
O=C1N(C(S2)=NC(N3CCNCC3)=C1)N=C2C4=CC(NC(CN)=O)=CN=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 386.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Plow EF, Das M. Rising like the phoenix? Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2182-3. doi: 10.1161/ATVBAHA.114.304486. PubMed PMID: 25231635; PubMed Central PMCID: PMC4198940. 2: Li J, Vootukuri S, Shang Y, Negri A, Jiang JK, Nedelman M, Diacovo TG, Filizola M, Thomas CJ, Coller BS. RUC-4: a novel αIIbβ3 antagonist for prehospital therapy of myocardial infarction. Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2321-9. doi: 10.1161/ATVBAHA.114.303724. Epub 2014 Aug 21. PubMed PMID: 25147334; PubMed Central PMCID: PMC4180209. 3: Vogt C, Hoffmann RD, Rodewald UCh, Eickerling G, Presnitz M, Eyert V, Scherer W, Pöttgen R. High- and low-temperature modifications of Sc3RuC4 and Sc3OsC4--relativistic effects, structure, and chemical bonding. Inorg Chem. 2009 Jul 20;48(14):6436-51. doi: 10.1021/ic9002143. PubMed PMID: 19522517.