Nonabine | CAS#16985-03-8 | antiemetic

MedKoo Cat#: 584264 | Name: Nonabine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nonabine is an antiemetic.

Chemical Structure

Nonabine

CAS#16985-03-8

Theoretical Analysis

MedKoo Cat#: 584264

Name: Nonabine

CAS#: 16985-03-8

Chemical Formula: C25H33NO2

Exact Mass: 379.2511

Molecular Weight: 379.54

Elemental Analysis: C, 79.11; H, 8.76; N, 3.69; O, 8.43

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Nonabine

IUPAC/Chemical Name

2H-1-Benzopyran-5-ol, 7-(1,2-dimethylheptyl)-2,2-dimethyl-4-(4-pyridyl)-

InChi Key

YHUDSHIRWOVVCV-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H33NO2/c1-6-7-8-9-17(2)18(3)20-14-22(27)24-21(19-10-12-26-13-11-19)16-25(4,5)28-23(24)15-20/h10-18,27H,6-9H2,1-5H3

SMILES Code

OC1=C2C(C3=CC=NC=C3)=CC(C)(C)OC2=CC(C(C)C(C)CCCCC)=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 379.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: McClelland GR, Sutton JA. Pilot investigation of the quantitative EEG and clinical effects of ketazolam and the novel antiemetic nonabine in normal subjects. Psychopharmacology (Berl). 1985;85(3):306-8. PubMed PMID: 2860687. 2: Staquet M, Bron D, Rozencweig M, Kenis Y. Clinical studies with a THC analog (BRL-4664) in the prevention of cisplatin-induced vomiting. J Clin Pharmacol. 1981 Aug-Sep;21(8-9 Suppl):60S-63S. PubMed PMID: 7197692. 3: Archer CB, Amlot PL, Trounce JR. Antiemetic effect of nonabine in cancer chemotherapy: a double blind study comparing nonabine and chlorpromazine. Br Med J (Clin Res Ed). 1983 Jan 29;286(6362):350-1. PubMed PMID: 6402096; PubMed Central PMCID: PMC1546960.