Noladin | CAS# 222723-55-9 | Biochemical

MedKoo Cat#: 576400 | Name: Noladin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Noladin is a cannabinoid CB1 receptor agonist.

Chemical Structure

Noladin

CAS#222723-55-9

Theoretical Analysis

MedKoo Cat#: 576400

Name: Noladin

CAS#: 222723-55-9

Chemical Formula: C23H40O3

Exact Mass: 364.2977

Molecular Weight: 364.57

Elemental Analysis: C, 75.78; H, 11.06; O, 13.17

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

HU-310; HU 310; HU310; Noladin; Noladin ether

IUPAC/Chemical Name

1,3-Propanediol, 2-((5Z,8Z,11Z,14Z)-5,8,11,14-eicosatetraenyloxy)-

InChi Key

CUJUUWXZAQHCNC-DOFZRALJSA-N

InChi Code

InChI=1S/C23H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26-23(21-24)22-25/h6-7,9-10,12-13,15-16,23-25H,2-5,8,11,14,17-22H2,1H3/b7-6-,10-9-,13-12-,16-15-

SMILES Code

CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCCOC(CO)CO

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 364.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Jones EK, Kirkham TC. Noladin ether, a putative endocannabinoid, enhances motivation to eat after acute systemic administration in rats. Br J Pharmacol. 2012 Jul;166(6):1815-21. doi: 10.1111/j.1476-5381.2012.01888.x. PMID: 22309979; PMCID: PMC3402806. 2. Duncan M, Millns P, Smart D, Wright JE, Kendall DA, Ralevic V. Noladin ether, a putative endocannabinoid, attenuates sensory neurotransmission in the rat isolated mesenteric arterial bed via a non-CB1/CB2 G(i/o) linked receptor. Br J Pharmacol. 2004 Jun;142(3):509-18. doi: 10.1038/sj.bjp.0705789. Epub 2004 May 17. PMID: 15148262; PMCID: PMC1574960. 3. Páldyová E, Bereczki E, Sántha M, Wenger T, Borsodi A, Benyhe S. Noladin ether, a putative endocannabinoid, inhibits mu-opioid receptor activation via CB2 cannabinoid receptors. Neurochem Int. 2008 Jan;52(1-2):321-8. doi: 10.1016/j.neuint.2007.06.033. Epub 2007 Jul 4. PMID: 17698254.