Monuron | CAS#150-68-5 | herbicide

MedKoo Cat#: 558111 | Name: Monuron

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Monuron is an herbicide, made up of white crystalline solid or white powder with a slight odor.

Chemical Structure

Monuron

CAS#150-68-5

Theoretical Analysis

MedKoo Cat#: 558111

Name: Monuron

CAS#: 150-68-5

Chemical Formula: C9H11ClN2O

Exact Mass: 198.0560

Molecular Weight: 198.65

Elemental Analysis: C, 54.42; H, 5.58; Cl, 17.85; N, 14.10; O, 8.05

Price and Availability

Size	Price	Availability	Quantity
100mg	USD 220.00
100mg	USD 220.00

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Related CAS #

No Data

Synonym

Lirobetarex; Monurex; Monuron; Monuroun; Monurox;

IUPAC/Chemical Name

Urea, 3-(p-chlorophenyl)-1,1-dimethyl-

InChi Key

BMLIZLVNXIYGCK-UHFFFAOYSA-N

InChi Code

InChI=1S/C9H11ClN2O/c1-12(2)9(13)11-8-5-3-7(10)4-6-8/h3-6H,1-2H3,(H,11,13)

SMILES Code

O=C(NC1=CC=C(Cl)C=C1)N(C)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

Monuron is an herbicide.

In vitro activity:

TBD

In vivo activity:

TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 198.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

1: Boucheloukh H, Sehili T, Kouachi N, Djebbar K. Kinetic and analytical study of the photo-induced degradation of monuron by nitrates and nitrites under irradiation or in the dark. Photochem Photobiol Sci. 2012 Aug;11(8):1339-45. doi: 10.1039/c2pp25044f. Epub 2012 Jun 1. PubMed PMID: 22659944. 2: Chu W, Rao YF. Photocatalytic oxidation of monuron in the suspension of WO3 under the irradiation of UV-visible light. Chemosphere. 2012 Mar;86(11):1079-86. doi: 10.1016/j.chemosphere.2011.11.062. Epub 2011 Dec 26. PubMed PMID: 22205047. 3: Hu Y. Simultaneous determination of phenylurea herbicides in yam by capillary electrophoresis with electrochemiluminescence detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Apr 1;986-987:143-8. doi: 10.1016/j.jchromb.2015.02.016. Epub 2015 Feb 17. PubMed PMID: 25732033. 4: Chu W, Chan KH, Jafvert CT, Chan YS. Removal of phenylurea herbicide monuron via riboflavin-mediated photosensitization. Chemosphere. 2007 Sep;69(2):177-83. Epub 2007 Jun 20. PubMed PMID: 17583771. 5: Voloshina LT. [Hygienic evaluation of translocation of the herbicides diuron and monuron]. Gig Sanit. 1984 Jul;(7):75. Russian. PubMed PMID: 6479634. 6: Monuron. IARC Monogr Eval Carcinog Risks Hum. 1991;53:467-80. Review. PubMed PMID: 1845379. 7: Chu W, Choy WK, Kwan CY. Selection of supported cobalt substrates in the presence of oxone for the oxidation of monuron. J Agric Food Chem. 2007 Jul 11;55(14):5708-13. Epub 2007 Jun 14. PubMed PMID: 17567139. 8: Kovács K, Farkas J, Veréb G, Arany E, Simon G, Schrantz K, Dombi A, Hernádi K, Alapi T. Comparison of various advanced oxidation processes for the degradation of phenylurea herbicides. J Environ Sci Health B. 2016;51(4):205-14. doi: 10.1080/03601234.2015.1120597. Epub 2016 Jan 14. PubMed PMID: 26764571. 9: Mest'ánková H, Mailhot G, Pilichowski JF, Krýsa J, Jirkovský J, Bolte M. Mineralisation of Monuron photoinduced by Fe(III) in aqueous solution. Chemosphere. 2004 Dec;57(10):1307-15. PubMed PMID: 15519375. 10: HODGE HC, MAYNARD EA, DOWNS WL, COYE RD. Chronic toxicity of 3-(p-chlorophenyl)-1,1-dimethylurea (monuron). AMA Arch Ind Health. 1958 Jan;17(1):45-7. PubMed PMID: 13486954. 11: National Toxicology Program . NTP Toxicology and Carcinogenesis Studies of Monuron (CAS No. 150-68-5) in F344/N Rats and B6C3F1 Mice (Feed Studies). Natl Toxicol Program Tech Rep Ser. 1988 Aug;266:1-166. PubMed PMID: 12748686. 12: Sellrie F, Warsinke A, Micheel B. Homogeneous indirect fluorescence quenching immunoassay for the determination of low molecular weight substances. Anal Bioanal Chem. 2006 Sep;386(2):206-10. Epub 2006 Jul 25. PubMed PMID: 16865334. 13: ROCHE J, ANDRE S. [ACTION OF 3-(P-CHLOROPHENYL)-1,1-DIMETHYLUREA (MONURON) ON IODIDE FIXATION BY A MARINE ALGA]. C R Seances Soc Biol Fil. 1964;158:493-7. French. PubMed PMID: 14193701. 14: Bobu M, Wilson S, Greibrokk T, Lundanes E, Siminiceanu I. Comparison of advanced oxidation processes and identification of monuron photodegradation products in aqueous solution. Chemosphere. 2006 Jun;63(10):1718-27. Epub 2005 Nov 9. PubMed PMID: 16289213. 15: Ernst W, Böhme C. [On metabolism of urea herbicides in the rat. I. Monuron and Aresin]. Food Cosmet Toxicol. 1965 Nov-Dec;3(5):789-96. German. PubMed PMID: 5887701. 16: Wang D, Mukome FN, Yan D, Wang H, Scow KM, Parikh SJ. Phenylurea herbicide sorption to biochars and agricultural soil. J Environ Sci Health B. 2015;50(8):544-51. doi: 10.1080/03601234.2015.1028830. PubMed PMID: 26065514; PubMed Central PMCID: PMC4838459. 17: SWEETSER PB. Photoinactivation of monuron, 3-(p-chlorophenyl)-1,1-dimethylurea, by riboflavin 5-phosphate. Biochim Biophys Acta. 1963 Jan 15;66:78-85. PubMed PMID: 13979678. 18: RAUD G, TYSSET C, VACHER B. [Studies on the anti-algal properties of 3-(p-chlorophenyl)-1, 1-dimethylurea (monuron, C. M. U.) in soil microbiology]. Ann Inst Pasteur (Paris). 1959 Feb;96(2):242-4. French. PubMed PMID: 13627591. 19: Donaldson TW, Bayer DE, Leonard OA. Absorption of 2,4-Dichlorophenoxyacetic Acid and 3-(p-Chlorophenyl)-1, 1-dimethylurea (Monuron) by Barley Roots. Plant Physiol. 1973 Dec;52(6):638-45. PubMed PMID: 16658621; PubMed Central PMCID: PMC366562. 20: Rubenchik BL, Botsman NE, Groban' GP. [The carcinogenic effect of the herbicide monuron]. Vopr Onkol. 1970;16(10):51-3. Russian. PubMed PMID: 4325192.