MedKoo Cat#: 527463 | Name: BRD2492
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BRD2492 is a potent, selective HDAC1 and HDAC2 inhibitor with IC50s of 13.2 nM and 77.2 nM, respecrtively.

Chemical Structure

BRD2492
BRD2492
CAS#1821669-43-5

Theoretical Analysis

MedKoo Cat#: 527463

Name: BRD2492

CAS#: 1821669-43-5

Chemical Formula: C20H18N4O2

Exact Mass: 346.1430

Molecular Weight: 346.39

Elemental Analysis: C, 69.35; H, 5.24; N, 16.17; O, 9.24

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
500mg USD 2,850.00 2 Weeks
1g USD 4,350.00 2 Weeks
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Related CAS #
Synonym
BRD2492; BRD-2492; BRD 2492;
IUPAC/Chemical Name
4-Acetylamino-N-(2-amino-5-pyridin-4-yl-phenyl)-benzamide
InChi Key
BBHURYMVPMFILR-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H18N4O2/c1-13(25)23-17-5-2-15(3-6-17)20(26)24-19-12-16(4-7-18(19)21)14-8-10-22-11-9-14/h2-12H,21H2,1H3,(H,23,25)(H,24,26)
SMILES Code
O=C(NC1=CC(C2=CC=NC=C2)=CC=C1N)C3=CC=C(NC(C)=O)C=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 346.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Schäker-Hübner L, Haschemi R, Büch T, Kraft FB, Brumme B, Schöler A, Jenke R, Meiler J, Aigner A, Bendas G, Hansen FK. Balancing Histone Deacetylase (HDAC) Inhibition and Drug-likeness: Biological and Physicochemical Evaluation of Class I Selective HDAC Inhibitors. ChemMedChem. 2022 May 4;17(9):e202100755. doi: 10.1002/cmdc.202100755. Epub 2022 Feb 18. PMID: 35073610; PMCID: PMC9303312.