IUPAC/Chemical Name
4,6,9-Trihydroxy-8-methyl-3,4-dihydro-2H-anthracen-1-one
InChi Key
LIETVYHJBSLSSW-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H14O4/c1-7-4-9(16)5-8-6-10-11(17)2-3-12(18)14(10)15(19)13(7)8/h4-6,11,16-17,19H,2-3H2,1H3
SMILES Code
O=C1CCC(O)C2=C1C(O)=C3C(C)=CC(O)=CC3=C2
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
258.27
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Wang XJ, Xiang ZD, Gong DL, Wang JD, Liu CX, Zhu ZX, Yan YJ, Xiang WS. A new okicenone analog from Streptomyces sp. NEAU-W13. J Antibiot (Tokyo). 2011 Jun;64(6):459-60. doi: 10.1038/ja.2011.22. Epub 2011 Mar 30. PubMed PMID: 21448189.
2: Meisner NC, Hintersteiner M, Mueller K, Bauer R, Seifert JM, Naegeli HU, Ottl J, Oberer L, Guenat C, Moss S, Harrer N, Woisetschlaeger M, Buehler C, Uhl V, Auer M. Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR. Nat Chem Biol. 2007 Aug;3(8):508-15. Epub 2007 Jul 15. PubMed PMID: 17632515.
3: Funayama S, Ishibashi M, Komiyama K, Omura S. A new antibiotic, okicenone. II. Physico-chemical properties and structure elucidation. J Antibiot (Tokyo). 1991 Aug;44(8):819-23. PubMed PMID: 1917696.
4: Komiyama K, Funayama S, Anraku Y, Ishibashi M, Takahashi Y, Kawakami T, Omura S. A new antibiotic, okicenone. I. Taxonomy, fermentation, isolation and biological characteristics. J Antibiot (Tokyo). 1991 Aug;44(8):814-8. PubMed PMID: 1917695.
