U46619 is a PGH2 (TXA2) analog that is a potent and stable thromboxane A2 (TP) receptor agonist (EC50 = 0.035 μM). U46619 potently stimulates TP receptor-mediated, but not other prostaglandin receptor-mediated responses in various in vitro preparations. It activates ERK-1 and ERK-2 in HEK 293 cells expressing TPα and TPβ receptors.
MedKoo Cat#: 532848
Name: U46619
CAS#: 56985-40-1
Chemical Formula: C21H34O4
Exact Mass: 350.2457
Molecular Weight: 350.50
Elemental Analysis: C, 71.96; H, 9.78; O, 18.26
The following data is based on the product molecular weight 350.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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