Synonym
Rufigallol; AI3-00865; AI3 00865; AI300865
IUPAC/Chemical Name
9,10-Anthracenedione, 1,2,3,5,6,7-hexahydroxy-
InChi Key
NEIMTOOWBACOHT-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H8O8/c15-5-1-3-7(13(21)11(5)19)10(18)4-2-6(16)12(20)14(22)8(4)9(3)17/h1-2,15-16,19-22H
SMILES Code
O=C1C2=C(C(O)=C(O)C(O)=C2)C(C3=CC(O)=C(O)C(O)=C13)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
304.21
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Mahajan SS, Kamath VR, Ghatpande SS. Synergistic antimalarial activity of ketones with rufigallol and vitamin C. Parasitology. 2005 Oct;131(Pt 4):459-66. PubMed PMID: 16174410.
2: Dvinskikh SV, Zimmermann H, Maliniak A, Sandström D. Heteronuclear dipolar recoupling in liquid crystals and solids by PISEMA-type pulse sequences. J Magn Reson. 2003 Sep;164(1):165-70. PubMed PMID: 12932469.
3: Dvinskikh SV, Zimmermann H, Maliniak A, Sandström D. Separated local field spectroscopy of columnar and nematic liquid crystals. J Magn Reson. 2003 Jul;163(1):46-55. PubMed PMID: 12852906.
4: Winter RW, Ignatushchenko M, Ogundahunsi OA, Cornell KA, Oduola AM, Hinrichs DJ, Riscoe MK. Potentiation of an antimalarial oxidant drug. Antimicrob Agents Chemother. 1997 Jul;41(7):1449-54. PubMed PMID: 9210664; PubMed Central PMCID: PMC163938.
5: Winter RW, Cornell KA, Johnson LL, Ignatushchenko M, Hinrichs DJ, Riscoe MK. Potentiation of the antimalarial agent rufigallol. Antimicrob Agents Chemother. 1996 Jun;40(6):1408-11. PubMed PMID: 8726010; PubMed Central PMCID: PMC163340.
6: Huang MT, Chang RL, Wood AW, Newmark HL, Sayer JM, Yagi H, Jerina DM, Conney AH. Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by tannic acid, hydroxylated anthraquinones and hydroxylated cinnamic acid derivatives. Carcinogenesis. 1985 Feb;6(2):237-42. PubMed PMID: 3918802.
