NDT9520492 | CAS#610297-00-2 | C5a receptor modulator

MedKoo Cat#: 532316 | Name: NDT9520492

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NDT9520492 is a C5a receptor modulator, which may be useful in the treatment of conditions associated with pathol. C5a receptor. activation,

Chemical Structure

NDT9520492

CAS#610297-00-2

Theoretical Analysis

MedKoo Cat#: 532316

Name: NDT9520492

CAS#: 610297-00-2

Chemical Formula: C38H35FN2O

Exact Mass: 554.2733

Molecular Weight: 554.71

Elemental Analysis: C, 82.28; H, 6.36; F, 3.42; N, 5.05; O, 2.88

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NDT9520492; NDT 9520492; NDT-9520492.

IUPAC/Chemical Name

(2S)-N-(2,3-dihydro-1H-inden-2-yl)-N-[(2-fluorophenyl)methyl]-2-[(1R)-1-naphthalen-1-yl-3,4-dihydro-1H-isoquinolin-2-yl]propanamide

InChi Key

OEINKGYXWSIVKM-KJICVINHSA-N

InChi Code

InChI=1S/C38H35FN2O/c1-26(38(42)41(25-31-15-6-9-20-36(31)39)32-23-29-13-2-3-14-30(29)24-32)40-22-21-28-12-5-8-18-34(28)37(40)35-19-10-16-27-11-4-7-17-33(27)35/h2-20,26,32,37H,21-25H2,1H3/t26-,37+/m0/s1

SMILES Code

C[C@H](N1[C@@H](C2=C3C=CC=CC3=CC=C2)C4=C(C=CC=C4)CC1)C(N(C5CC6=C(C=CC=C6)C5)CC7=CC=CC=C7F)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Anaphylatoxin C5a is a potent inflammatory mediator associated with pathogenesis and progression of several inflammation-associated disorders. Small mol. C5a receptor (C5aR) antagonist development is hampered by species-specific receptor biol. and the associated inability to use standard rat and mouse in vivo models. Gerbil is one rodent species reportedly responsive to small mol. C5aR antagonists with human C5aR affinity.

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 554.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.