MedKoo Cat#: 528303 | Name: RDEA-427

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RDEA-427 is a non-nucleoside reverse transcriptase inhibitor potentially for the treatment of HIV infection.

Chemical Structure

RDEA-427
RDEA-427
CAS#914496-19-8

Theoretical Analysis

MedKoo Cat#: 528303

Name: RDEA-427

CAS#: 914496-19-8

Chemical Formula: C22H16N6O

Exact Mass: 380.1386

Molecular Weight: 380.41

Elemental Analysis: C, 69.46; H, 4.24; N, 22.09; O, 4.21

Price and Availability

This product was removed for the commercial reasons.
Related CAS #
No Data
Synonym
RDEA-427; RDEA 427; RDEA427
IUPAC/Chemical Name
4-((2-((4-cyanophenyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile
InChi Key
PFGKQRWHIVJCSQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H16N6O/c1-13-9-16(12-24)10-14(2)19(13)29-21-18-7-8-25-20(18)27-22(28-21)26-17-5-3-15(11-23)4-6-17/h3-10H,1-2H3,(H2,25,26,27,28)
SMILES Code
N#CC1=CC(C)=C(OC2=C3C(NC=C3)=NC(NC4=CC=C(C#N)C=C4)=N2)C(C)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 380.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL