MedKoo Cat#: 531554 | Name: BMS270394
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

BMS270394 is a nuclear retinoic acid receptor (RAR-γ) agonist. It is a more active enantiomer of BMS 189961.

Chemical Structure

BMS270394
CAS#262433-54-5

Theoretical Analysis

MedKoo Cat#: 531554

Name: BMS270394

CAS#: 262433-54-5

Chemical Formula: C23H26FNO4

Exact Mass: 399.1846

Molecular Weight: 399.46

Elemental Analysis: C, 69.16; H, 6.56; F, 4.76; N, 3.51; O, 16.02

Price and Availability

Size Price Availability Quantity
5mg USD 385.00 2 Weeks
25mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
BMS270394; BMS-270394 ; BMS 270394; BMS 189961.
IUPAC/Chemical Name
3-fluoro-4-[[(2R)-2-hydroxy-2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)acetyl]amino]benzoic acid
InChi Key
AANFHDFOMFRLLR-LJQANCHMSA-N
InChi Code
InChI=1S/C23H26FNO4/c1-22(2)9-10-23(3,4)16-11-13(5-7-15(16)22)19(26)20(27)25-18-8-6-14(21(28)29)12-17(18)24/h5-8,11-12,19,26H,9-10H2,1-4H3,(H,25,27)(H,28,29)/t19-/m1/s1
SMILES Code
O=C(O)C1=CC=C(NC([C@H](O)C2=CC=C3C(C)(C)CCC(C)(C)C3=C2)=O)C(F)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 399.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Klaholz BP, Mitschler A, Belema M, Zusi C, Moras D. Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma. Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6322-7. PubMed PMID: 10841540; PubMed Central PMCID: PMC18601.