Doxacurium Chloride | Nuromax | BW-A-938U | CAS#106819-53-8 | Muscarinic Acetylcholine Receptor M2 Antagonist

MedKoo Cat#: 329006 | Name: Doxacurium Chloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Doxacurium Chloride, also known as Nuromax and BW-A-938U, is a muscarinic acetylcholine receptor M2 antagonist which has been shown to be devoid of cardiovascular side effects when administered in modest doses. Doxacurium Chloride is minimally hydrolyzed by human plasma cholinesterase.

Chemical Structure

Doxacurium Chloride

CAS#106819-53-8 (chloride)

Theoretical Analysis

MedKoo Cat#: 329006

Name: Doxacurium Chloride

CAS#: 106819-53-8 (chloride)

Chemical Formula: C56H78Cl2N2O16

Exact Mass:

Molecular Weight: 1106.14

Elemental Analysis: C, 60.81; H, 7.11; Cl, 6.41; N, 2.53; O, 23.14

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

133814-18-3 (free base) 106819-53-8 (chloride)

Synonym

Doxacurium Chloride; Nuromax; BW-A-938U; BW A 938U; BWA938U;

IUPAC/Chemical Name

(1S,2R)-6,7,8-trimethoxy-2-methyl-2-(3-((4-oxo-4-(3-((1R,2S)-6,7,8-trimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium-2-yl)propoxy)butanoyl)oxy)propyl)-1-(3,4,5-trimethoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-2-ium chloride

InChi Key

APADFLLAXHIMFU-LGIHQUBZSA-L

InChi Code

InChI=1S/C56H78N2O16.2ClH/c1-57(23-19-37-33-45(65-7)53(69-11)55(71-13)49(37)39(57)27-35-29-41(61-3)51(67-9)42(30-35)62-4)21-15-25-73-47(59)17-18-48(60)74-26-16-22-58(2)24-20-38-34-46(66-8)54(70-12)56(72-14)50(38)40(58)28-36-31-43(63-5)52(68-10)44(32-36)64-6;;/h29-34,39-40H,15-28H2,1-14H3;2*1H/q+2;;/p-2/t39-,40+,57-,58+;;

SMILES Code

COC1=CC(C[C@@H]2C3=C(C=C(C(OC)=C3OC)OC)CC[N@+]2(CCCOC(CCC(OCCC[N@+]4(CCC5=CC(OC)=C(C(OC)=C5[C@@H]4CC6=CC(OC)=C(OC)C(OC)=C6)OC)C)=O)=O)C)=CC(OC)=C1OC.[Cl-].[Cl-]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,106.14 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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